组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2014, Vol. 10 ›› Issue (4): 236-239.doi: 10.3969/j.issn.1673-0364.2014.04.018

• 综述 • 上一篇    下一篇

脂肪间充质干细胞治疗皮肤老化的研究进展

刘美辰，刘霞，肖苒，曹谊林   

  1. 中国医学科学院整形外科医院研究中心
  • 发布日期:2020-07-23

The Role of Adipose-derived Stem Cells in Skin Aging Treatment

LIU Meichen,LIU Xia,XIAO Ran,CAO Yilin   

  1. Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College;
  • Published:2020-07-23

摘要： 脂肪间充质干细胞(Adipose-Derived Stem Cells,ADSC)是来源于脂肪组织的多能干细胞,具有自我更新和多向分化能力,并能分泌多种生物活性因子,在组织损伤、修复方面蕴含着广阔的应用前景。近年来,ADSC在抗皮肤老化方面的作用也被证实。本文就ADSCs在皮肤抗皱、美白、促进毛发再生、增强组织修复能力等方面的研究现况进行综述。

关键词: 脂肪间充质干细胞, 皮肤老化, 旁分泌, 抗氧化

Abstract: Adipose-derived stem cells (ADSC), cating in fat tissue, pluripotent mesenchymal stem cells which display the ability of self-renewal and multi-lineage differentiation and can secrete a variety of biological activity factors, having broad application prospects in regenerative medicine. Recently, diverse rejuvenation effects of ADSCs on skin have been demonstrated. The role of ADSCs in anti-wrinkle, whitening, promoting hair regeneration, improving the ability of tissue repair were reviewed in this paper.

Key words: Adipose-derived stem cells, Skin aging, Paracrine, Antioxidant

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