Journal of Tissue Engineering and Reconstructive Surgery ›› 2009, Vol. 5 ›› Issue (4): 205-207.doi: 10.3969/j.issn.1673-0364.2009.08.007

• Original article • Previous Articles     Next Articles

Effect of L-arginine on the Wound Healing of Diabetic Mice

CHEN Xiaohua1,YU Pan2,LI Shirong2,WANG Zhenxiang2   

  1. 1 Shanghai Time Plastic Surgery Hospital;Shanghai 200021;China;2 Department of Plastic Surgery;Southwest Hospital;Third Military Medical University;Chongqing 400038;China.;
  • Published:2020-07-23

Abstract: Objective To investigate the effect of L-arginine used in the wound of mice with diabetes. Methods Type IDM mice induced by streptozotocin were used as the animal model. Seventy five male KM mice were used in this study and were randomly divided into group A (normal control, n=25), group B (diabetic control, n=25) and group C (diabetes with L- arginine administration, n=25). The percentage of healing areas, the granulation tissue formation, the histological and morphological changes and the content of hydro...

Key words: Diabetes, L-arginine, Wound healing, Nitric Oxide

CLC Number: