Journal of Tissue Engineering and Reconstructive Surgery ›› 2014, Vol. 10 ›› Issue (6): 339-342.doi: 10.3969/j.issn.1673-0364.2014.06.010

• Original article • Previous Articles     Next Articles

Evaluation on Two Kinds of Cell-assisted Lipotransfer for Breast Augmentation

WANG Lin,LU Yi,FU Mingang,HE Jiyin,HUANG yixiong,FAN Zhihong   

  1. Department of Aesthetic and Plastic Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine;
  • Published:2020-07-23

Abstract: Objective To evaluate the effect of two kinds of cell-assisted lipotransfer for breast augmentation. Methods Thirty patients accepted breast augmentation using cell-assisted lipotransfer (CAL), and completed 12-month follow-up. According to the stromal vascular fraction (SVF) distilled from adipose tissue or aspirated liquid, the patients were divided into 2 groups:S group and L group. Flow-cytometry was used to detect the percentage of adipose-derived stem cells (ADSCs) in distilled SVF. The breast volumes and images were evaluated by MRI pre-operative, 6 and 12 months post-operative. The data of breast volume were marked and the resorption rate of transplanted adipose tissue was calculated. Results Averagely, the percentage of ADSCs in freshly distilled SVF in S group is 40.73% and 3.75% in L group. MRI showed that the breast volume 6-month post-operative and 12-month post-operative were both larger than that of preoperative in S group (P〈0.05), while no significant difference between the breast volume 6-month post-operative and 12-month post-operative were observed (P〉0.05), neither the resorption rate of 6 and 12-month post-operative (P〉0.05), and the resorption rate of transplanted adipose tissue 12-month post-operative in S group was (51.83±15.28)%. However, there were no significant difference of breast volume among three time points in L group (P〉0.05), neither the resorption rate of 6 and 12-month post-operative (P〉0.05), and the resorption rate of transplanted adipose tissue 12-month post-operative in L group was (75.47±12.20)%. In addition, no calcification was seen in all MRI images but cysts were found in two cases of S group. Conclusion In process of breast augmentaion using cell-assissted lipotransfer, the distilled SVF from adipose tissue contains more ADSCs than that from aspirated liquid. The cell-assisted lipotransfer for breast augmentation is effective, safe, and the shrinkage stalls at 6-month post-operative.

Key words: Cell-assissted lipotransfer, Breast augmentation, Breast volume

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