Journal of Tissue Engineering and Reconstructive Surgery ›› 2015, Vol. 11 ›› Issue (4): 258-260.doi: 10.3969/j.issn.1673-0364.2015.04.010

• Original article • Previous Articles     Next Articles

Observation on the Efficacy of Skin Grinding Combined with External Application of Recombinant Human Basic Fibroblast Growth Factor in the Treatment of Superficial Scars

LI Zhiming,CHAI Yong,QIAN Niwen,HUANG Yuanfa,FANG Yunde   

  • Published:2020-07-23

Abstract: Objective To explore the clinical efficacy of skin grinding combining with external application of recombinant human basic fibroblast growth factor (rh-bFGF) in the treatment of superficial scar. Methods From February 2010 to March 2015, 23 patients with superficial scar were treated with dermabrasion, then the wound was covered with vaseline gauze that accompanied by rh-bFGF solution, and bandaged. Follow-up and curative effect evaluation were carried out after operation. Results After treatment, markedly effective results were observed in 18 cases, effective results were observed in 3 cases, ineffective results were observed in 2 cases, and the effective rate was 90.9%. All the patients were followed up for 1 to 8 months. The wound showed different degree of erythema and pigmentation after operation, and all of them obtained satisfactory results through active nursing and treatment. Conclusion Skin grinding combining with external application of rh-bFGF can reduce the time of wound healing and inhibit the formation of scar tissue, the curative effect is reliable.

Key words: Dermabrasion, Superficial scar, Recombinant human basic fibroblast growth factor

CLC Number: