Abstract:

　Diabetic foot ulceration (DFU) is a common complication in diabetic patients and an important cause of

deterioration, amputation and even death. Thorough debridement, infection control, re-establishment of blood flow and timely

repair of the wound are the mainstays of treatment for DFU. Antibiotic bone cement has been used to treat DFU wounds with

satisfactory results. In this paper, the available literature was analyzed and found that the common strategy for the use of

antibiotic bone cement in DFU is to cover the wound with antibiotic bone cement to control infection and promote induction

membrane production after complete debridement in phase 1, and to repair the wound with skin grafting, flap grafting and Ilizarov

technique in phase 2. In addition, the relevant adjuvant treatments were listed based on antibiotic bone cement materials to

provide a variety of options for clinical treatment.

Key words:

　Diabetic foot ulcer, 　Antibiotic bone cement, 　Debridement, 　Infection