Objective To explore the clinical efficacy of traditional Chinese medicine external treatment for the repair of refractory wounds in the limbs. Methods Patients were divided into two groups according to treatment methods. The observation group received traditional Chinese medicine external treatment with Zigui Zhangpi ointment combined with moxibustion， while the control group received treatment with growth factor combined with vaseline oil gauze. The clinical efficacy of the two groups was retrospectively analyzed. Results A total of 67 cases were collected， including 35 in the observation group and 32 in the control group. After treatment， all the wounds healed， and the average healing time in the observation group was （43.94±24.92） days， shorter than （62.03±64.88） days in the control group， but with no statistically significant difference （P>0.05）. The rate of healing within 2 months were 82.86% and 59.38% in the observation group and control group， respectively， and the difference was statistically significant （P<0.05）. Before treatment， the average wound area of the observation group and the control group were （10.93±14.93） cm2 and （8.13±7.53） cm2 ， respectively. And 30 daysafter treatment， the wound area of the observation group and the control group were （2.61±6.91） cm2 and （2.66±4.34） cm2 ，respectively. It was found that with the change of treatment time， the rate of wound reduction was significantly faster in the

observation group. After treatment， the visual analogue scale （VAS） score of pain in the observation group was 0.86±0.91，

significantly lower than that in the control group （1.25±0.51，P<0.05）.After one month of wound healing， the Vancouver

scar scale （VSS） score of the observation group was 3.45±1.82， significantly lower than that of the control group（4.81±1.54，P<0.05）.Conclusion Traditional Chinese medicine external treatment can shorten the treatment time of refractory wounds in the limbs， reduce the pain of patient， and inhibit scar formation.

Traditional Chinese medicine external treatment, Refractory wounds, Traditional Chinese medicine,