Sterilization methods for biomaterials in biomedical applications

Abstract

Abstract:

From the first generation of inert materials to the third generation of active materials， biomaterials have

developed rapidly in recent years， showing great application prospects in biomedicine， but its effective sterilization has

become increasingly difficult. Effective sterilization and disinfection of biomaterials are essential to achieve clinical

transformation. This review summarized the classical and emerging sterilization methods for biomaterials and the impact of

these sterilization technologies on the physicochemical properties of biomaterials. This review also discussed the sterilization

effect， toxicity， and problems in the practical application of various methods， intending to provide a reference for the

selection of sterilization methods in the research of biomaterials.

Key words:

Biomaterials, Hydrogel, Decellularized extracellular matrix, Sterilization

WU Ke, ZHANG Guo, ZHOU Muran, et al. Sterilization methods for biomaterials in biomedical applications[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2024, 20(3): 354-.

[1]	ZHANG Canxuan, FENG Yujin, HE Qiyuan, et al. Application and advances of double network hydrogel in the field of medicine and health [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2024, 20(1): 135-.
[2]	YANG Yan, SHANG Ying, LYU Qiang, et al. Treatment of rabbit ear hypertrophic scar by CO2 fractional laser-assisted silk nanofiber hydrogel-loaded asiaticoside　 [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2022, 18(3): 227-.
[3]	LIU Minglu, JIANG Sihan, TAN Yao, et al. Study on construction of myocardial microtissue in vitro by novel gelatin hydrogel combined with human induced pluripotent stem cell derived cardiomyocytes　 [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2022, 18(3): 219-.
[4]	DU Lin, LU Wenli, ZHANG Xiaoxu, et al（. Preparation and biological properties of double crosslinked high strength silk fibroin hydrogel [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2022, 18(2): 108-.
[5]	PI Qingmeng,WANG Xiaolei,ZHANG Zhiliang,ZHOU Biyu,REN Xiaoyun,LU Yi,HUANG Yixiong,FU Mingang,FAN Zhihong. Preliminary Application of Urethral Tissue Construction with Multiple Layers Using 3D Bio -printing [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2018, 14(5): 241-244.
[6]	LIANG Qian,ZHU Feiyan,HUANG Jianghong,WANG Daping,XIONG Jianyi. Research Progress of Type H Collagen Hydrogel in Cartilage Injury [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2017, 13(4): 228-231.
[7]	LI Pengfei,ZHENG Danning,YU Li. Treatment after Breast Augmentation with Polyacrylamide Hydrogel Injection [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2015, 11(2): 83-86.
[8]	YIN Zongqi,LI Ping,LI Dan,LIU Yi,WANG Zhenxing,LIU Yu,FENG Chuanliang,ZHOU Guangdong. Low-Molecule-Weight Hydrogel M2 and Cross-Lincked Hyaluronic Acid as Injectable Cartilage Regeneration Scaffolds [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2014, 10(6): 305-313.
[9]	LIANG Zhiwei,HUANG Zechun,TAN Zhangmei,ZHANGAnli,PENG li,WANG Hongmei. Clinical Analysis of Augmentation Mammaplasty by Implanting Silicon-gel Prosthesis Following the Removing of Polyacrylamide Hydrogel Through Peri-areolar Approach [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2008, 4(6): 341-343.
[10]	WANG Fengqi,GAO Fulei. Clinical Analysis of Removement of Injecting Polyacrylamide Hydrogel Through the Mammary Areolar Incision in 60 Cases [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2008, 4(6): 339-340.

Sterilization methods for biomaterials in biomedical applications

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 10

Recommended Articles

Metrics

Comments