Journal of Tissue Engineering and Reconstructive Surgery ›› 2025, Vol. 21 ›› Issue (5): 495-.

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Research on the mechanism and application of mechanical stimulation in tendon injury repair

  

  • Online:2025-10-13 Published:2025-10-30

Abstract:

Tendon injury is a common problem in the fields of sports medicine, joint orthopedics and plastic surgery. Its
repair process is complex and prone to incomplete functional recovery, involving the participation of multiple cells and the interaction between various molecules. Due to the lack of vascular supply and less metabolic activity of tendons, their regenerative capacity is limited. Therefore, tendon injury repair is currently a formidable challenge in the medical field. In recent years, mechanical force stimulation, as an important physical intervention method, has been widely studied and applied in the repair of tendon injuries. During the process of tendon injury repair, mechanical force stimulation can promote the regeneration and functional recovery of tendons through multiple mechanisms of action, such as regulating cell behavior, influencing inflammatory responses, improving tissue structure, and promoting angiogenesis. In this paper, the mechanism and application research of mechanical stimulation in tendon injury repair were reviewed.

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