Diabetic refractory cutaneous wounds， as one of the most severe complications of diabetes mellitus， present

complex pathogenesis primarily attributed to persistent hyperglycemia， micro-circulatory dysfunction， infection， and dysregulated inflammatory responses. Characterized by prolonged non-healing properties， these wounds not only significantly impair patients’ quality of life but also pose a major therapeutic challenge in current diabetes management. In recent years， bioactive glass has garnered increasing attention in soft tissue repair applications due to its unique bio-compatibility， proangiogenic properties， and antimicrobial efficacy. In this paper， recent advances in the application of bioactive glasses with different morphologies for diabetic wound treatment were reviewed， aiming to provide novel insights for optimizing therapeutic strategies for diabetic wound healing.

Bioactive glass, Diabetic skin wounds, Wound healing, Dressing