Abstract: Objective To investigate the effects of compound prescription of traditional Chinese medicine-lymph Fang on the treatment of chronic extremity lymphedema. Methods From September 2011 to December 2014, 239 patients with chronic extremity lymphedema were taken compound Chinese medical lymph Fang orally. The extent of tissue edema were detected by Multiple-frequency bioelectrical impedance analysis before and after treatment. The circumference of the extremities were measured before and after treatment. Results After treated for one course, remarkable reduction of accumulated edema fluid in tissue and circumference were observed （P〈0.05, P〈0.05）. On long-term follow-up, most of the patients felt better. The erysipelas seizure of frequency were decreased significantly. The correlation between edema lessening and circumference reducing was obviously significant （r=0.738, P〈0.01）. Conclusion Compound Chinese medical lymph Fang can effectively reduce the edema of extremities.

Key words: Lymphedema, Pharmacotherapy, Lymph Fang, Detumescence, Clinical efficacy