Abstract: Objective To explore the effect of ultrasound-guided EVLA in the treatment of Klippel-Trenaunay syndrome （KTS）. Methods A retrospective analysis were made for 47 KTS patients treated with EVLA from March 2007 to December 2010, and they were followed up for 0.5-5 years. Results After the EVLA and ligation treatment of varicose veins and KT veins for 2 weeks, blood flrw was not detected. After 6 months of treatment, blood flow of 45 cases （95%） was still closed. Local recurrence of varicose veins was observed in 2 cases. And after 1 year and later, local recurrence of varicose veins was observed in 9 cases. The superficial varicose veins and KT veins of other patients disappeared completely or only minor fibrous tissue was left, in which blood flow was not detected. Most of the treated veins became fibrous cords, and were hard to identify. No serious adverse reaction was observed. Conclusion Ultrasound-guided EVLA is a safe, simple and effective method for the treatment of varicose veins and KT veins in KTS patients.

Key words: Klippel-Trenaunay syndrome, Ultrasound, Laser treatment