Skin Sensitization Test of Silk Fibroin-based Nerve Guidance Conduit

doi:10.3969/j.issn.1673-0364.2009.01.008

Abstract

Abstract: Objective To study the sensitization of silk fibroin-based nerve guidance conduits (SF-NGCs) in vitro. Methods According to ISO 10993-10:1995 standard, maximization test was conducted in guinea pig. The skin sensitization reactions, including erythema and oedema, induced by SF-NGCs, normal saline and formalin solution were observed and scored respectively at 24, 48 and 72 h exposure of the infusion of the materials. The allergenic rates and mean response score were calculated. Results The allergenic rates a...

Key words: Silk Fibroin-based Nerve Guidance Conduit, Biocompatibility, Skin Sensitization Test

CLC Number:

R392-33

YAN Xiaoli,ZHAO Yahong,ZHAO Weijia,YANG Yumin. Skin Sensitization Test of Silk Fibroin-based Nerve Guidance Conduit[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(1): 29-31.

[1]	DU Lin, LU Wenli, ZHANG Xiaoxu, et al（. Preparation and biological properties of double crosslinked high strength silk fibroin hydrogel [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2022, 18(2): 108-.
[2]	YANG Chen, YAN Guozheng, ZHOU Zerun, HUA Fangfang. Biocompatibility and Biosafety Analysis of Transcutaneous Energy Transfer System of Artificial Anal Sphincter [J]. Journal of Shanghai Jiao Tong University, 2021, 55(9): 1151-1157.
[3]	XU Qiming,ZHOU Shengbo,MAO Hailei,WANG Bin. Testing Methods for the Biological Performance of Antibacterial Materials [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2015, 11(6): 386-395.
[4]	RONG Xicang, ZHANG Yu, TAN GnoXin, TAN Ying, NING Chengyun, LI Mei, LI Lihua. The Influen ce of Reaction Time on the Biocompatibility of Polydopamine/Silver Nanoparticles Modified Porous Titanium [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2015, 11(5): 295-319，326.
[5]	DING Chao, LI Qi, LIN Lijun, SUN Yongjian. Biocompatibility and Biosafety Research of New Compound of Fibrin Glue and Calcium Phosphate Bone Cement [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2015, 11(5): 301-304.
[6]	XU Lizhang,YU Jiangming,LI Kai,ZHENG Xuebin,DENG Guoying,WANG Weiheng,HUANG Xiaodong,YE Xiaojian. The Biocompatibility of Zinc-modified CaSiO3 Bioceramic Coating in vitro [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2015, 11(4): 229-233.
[7]	YAO Haijun,ZHAO Yang,ZHOU Zhe,XIAO Dongdong,ZHOU Juan,ZHANG Ming,WANG Zhong,HE Chuanglong,LU Mujun. Biocompatibility on Human Adipose-Derived Stem Cells Co-cultured with Poly-L-lactide/Polycaprolactone Scaffold [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2014, 10(5): 255-258.
[8]	FANG Zhengdong,HU Hejie,DONG Zhihui,WANG Xiaotian,SUN Xiaojie,GE Xinbao. Establish ment and Biocompatibility of a Small Diameter Tubular Scaffold of Electrospun Poly (L-lactide-co-ε-caprolactone)/fibrinogen Blended Fibers [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2014, 10(4): 207-210.
[9]	KE Lei1,YAN Guozheng1,LIU Zhiqiang1,YAN Sheng1,WANG Zhiwu1,WANG Yongbing2. In Vivo Research of Performance and Biocompatibility of an Artificial Anal Sphincter [J]. Journal of Shanghai Jiaotong University, 2014, 48(02): 193-198.
[10]	JIANG Jia1 (蒋佳), HAO Wei2 (郝威), LI Yu-zhuo1 (李毓卓), CHEN Jun3* (陈俊),YAO Jin-rong3 (姚晋荣), SHAO Zheng-zhong2 (邵正中), Li Hong1 (李宏),YANG Jian-jun1 (杨建军), CHEN Shi-yi1* (陈世益). Biocompatibility Evaluation of Polyethylene Terephthalate Artificial Ligament Coating Hydroxyapatite by Fibroblasts Cells in Vitro [J]. Journal of shanghai Jiaotong University (Science), 2012, 17(6): 717-722.
[11]	CAO Ning1* (曹宁), WANG Wen-bo2 (王文波), DONG Jian-wen2 (董建文). Animal Experiment of Viscose Carbon Fiber Based C/C Composites Applied in Bone Fracture Intramedullary Fixation [J]. Journal of shanghai Jiaotong University (Science), 2012, 17(5): 537-540.
[12]	LIU Jianbin. Experimental Study on Chitosan-Gelatin/β-Tricalcium Complex as Novel Scaffolds for Cartilage Tissue Engineering [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2010, 6(6): 319-322.
[13]	ZHANG Yanqing,ZENG Yuanshan,HE Liumin,QUAN Daping,LI Yan. Research Biocompatibility of the Poly(l-lactic acid) Nano-fibrous Scaffolds with Spinal Cord Tissues in Rats [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(3): 143-147.
[14]	WU Jian,YAN Xiaoli,ZHAO Yahong,YANG Yuming. Preliminary Study on the Biocompatibility of the Silk Fibroin Conduits-Based Nerve Grafts [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(2): 86-88.
[15]	WANG Dechao,LI Kui,CUI Bing,NING Yu,CHENG Feng. The Biocompatibility Study of Antigen-Extracted Xenogeneic Cancellous Bone Matrix [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(1): 32-34.

Skin Sensitization Test of Silk Fibroin-based Nerve Guidance Conduit

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments