Experimental Study on Tissue Engineered Blood Vessel with Bioreactor

doi:10.3969/j.issn.1673-0364.2009.06.005

Abstract

Abstract: Objective To investigate the feasibility of constructing tissue engineered blood vessels with bioreactor.Methods Cell-PGA(polyglycolic acid) complex was constructed by seeding smooth muscle cells(SMCs) isolated from canine carotid artery on PGA unwoven fibers.The cell-PGA complex was cultured in a bioreactor(pulse rate:75 /min,radical distension<5%).Eight weeks after culture in vitro,Endothelial cells(ECs) isolated from canine carotid vein were seeded on PGA and cultured for another 5 days.The control gr...

Key words: Tissue engineering, Bioreactor, Blood vessel, Reconstruction

CLC Number:

Q813.1+2

XU Zhicheng,ZHANG Wenjie,LI Hong,ZHOU Guangdong,CUI Lei,LIU Wei,CAO Yilin. Experimental Study on Tissue Engineered Blood Vessel with Bioreactor[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(3): 134-137.

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Experimental Study on Tissue Engineered Blood Vessel with Bioreactor

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