Journal of Tissue Engineering and Reconstructive Surgery ›› 2025, Vol. 21 ›› Issue (6): 599-.

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Application progress of silicone gel combined with photoelectric technology in the prevention and treatment of hypertrophic scars

  

  • Online:2025-12-25 Published:2025-12-30

Abstract:

Pathological scars represent an aberrant fibrotic repair outcome following deep dermal injuries. Among them,
the incidence of hypertrophic scars is relatively high, commonly seen after burns, surgical operations and cesarean sections. These scars significantly impair patients' quality of life due to associated pruritus, pain, and functional impairment. Silicone gel has emerged as a preferred therapeutic option for hypertrophic scars and keloids, owing to its well-established safety, efficacy, and ease of use. Recent studies have demonstrated that combining silicone gel with photoelectric technologies synergistically enhances therapeutic outcomes. This review consolidates evidence-based data to evaluate the efficacy and safety of silicone gel monotherapy and its combination with photoelectric therapies across diverse clinical populations, including medical aesthetics, burn rehabilitation, surgical procedures, cesarean section scars, and pediatric scar management. Furthermore, it discusses key clinical considerations and practical recommendations to advance personalized scar management strategies.

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