Abstract: In the framework of Relevance theory, the current study, based on written corpus of English native speakers, explored firstly the syntactic features of four DMs, also, too, as well, not...either, which signal the relationship of adding, for example, the frequency of the four DMs in different positions of a sentence, and that of the four DMs associate with comma; and explored the similarities and differences between the four in syntactic features, and the different contextual effects of different syntactic forms might cause. Then, the study investigated the using states of different learners from different regions of China, similarities and differences; whether the syntactic features are similar with that of natives, and what the misusing types are, and at the same time, analyzed briefly the reasons why some misusing type occurred more frequently, and why learners from some regions can generally grasped the DMs. From the findings in this research, learners might get a deeper understanding toward the systematic features of these four DMs, and clearly realize the using preference of the learners from their own region, thereby, obtain a reliable reference for their own acquisition.