产KPC型碳青霉烯酶肺炎克雷伯菌流行现状及分子遗传学研究进展

doi:10.16150/j.1671-2870.2017.05.018

摘要/Abstract

中图分类号:

R915

沈平华, 陈慧芬. 产KPC型碳青霉烯酶肺炎克雷伯菌流行现状及分子遗传学研究进展[J]. 诊断学理论与实践, 2017, 16(05): 544-548.

[1] Yigit H, Queenan AM, Anderson GJ, et al.Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae[J]. Antimicrob Agents Chemother,2001,45(4):1151-1161.
[2] Kuehn BM."Nightmare" bacteria on the rise in US hospitals, long-term care facilities[J]. JAMA,2013,309(15):1573-1574.
[3] McKenna M. Antibiotic resistance: the last resort[J]. Nature,2013,499(7459):394-396.
[4] Munoz-Price LS, Poirel L, Bonomo RA, et al.Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases[J]. Lancet Infect Dis,2013,13(9):785-796.
[5] Endimiani A, Depasquale JM, Forero S, et al.Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system[J]. J Antimicrob Chemother,2009,64(5):1102-1110.
[6] Naas T, Nordmann P, Vedel G, et al.Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC in a Klebsiella pneumoniae isolate from France[J]. Antimicrob Agents Chemother,2005,49(10):4423-4424.
[7] Munoz-Price LS, Poirel L, Bonomo RA, et al.Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases[J]. Lancet Infect Dis,2013,13(9):785-796.
[8] Weterings V, Zhou K, Rossen JW, et al.An outbreak of colistin-resistant Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae in the Netherlands (July to December 2013), with inter-institutional spread[J]. Eur J Clin Microbiol Infect Dis,2015,34(8):1647-1655.
[9] Kanerva M, Skogberg K, Ryynänen K, et al. Coincidental detection of the first outbreak of carbapenemase-producing Klebsiella pneumoniae colonisation in a primary care hospital, Finland, 2013[J]. Euro Surveill,2015,20(26)pii:21172.
[10] Wei ZQ, Du XX, Yu YS, et al.Plasmid-mediated KPC-2 in a Klebsiella pneumoniae isolate from China[J]. Antimicrob Agents Chemother,2007,51(2):763-765.
[11] Bradford PA, Bratu S, Urban C, et al.Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City[J]. Clin Infect Dis,2004,39(1):55-60.
[12] Hossain A, Ferraro MJ, Pino RM, et al.Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp[J]. Antimicrob Agents Chemother,2004,48(11):4438-4440.
[13] Chiang T, Mariano N, Urban C, et al.Identification of carbapenem-resistant klebsiella pneumoniae harboring KPC enzymes in New Jersey[J]. Microb Drug Resist,2007, 13(4):235-239.
[14] Pope J, Adams J, Doi Y, et al. KPC type beta-lactamase, rural Pennsylvania[J]. Emerg Infect Dis,2006,12(10):1613-1614.
[15] Smith Moland E, Hanson ND, Herrera VL, et al.Plasmid-mediated, carbapenem-hydrolysing beta-lactamase, KPC-2, in Klebsiella pneumoniae isolates[J]. J Antimicrob Chemother,2003,51(3):711-714.
[16] Kitchel B, Rasheed JK, Patel JB, et al.Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258[J]. Antimicrob Agents Chemother,2009,53(8):3365-3370.
[17] Tibbetts R, Frye JG, Marschall J, et al.Detection of KPC-2 in a clinical isolate of Proteus mirabilis and first reported description of carbapenemase resistance caused by a KPC beta-lactamase in P. mirabilis[J]. J Clin Microbiol,2008,46(9):3080-3083.
[18] Rasheed JK, Biddle JW, Anderson KF, et al.Detection of the Klebsiella pneumoniae carbapenemase type 2 Carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid[J]. J Clin Microbiol,2008,46(6):2066-2069.
[19] Robledo IE, Aquino EE, Vázquez GJ.Detection of the KPC gene in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii during a PCR-based nosocomial surveillance study in Puerto Rico[J]. Antimicrob Agents Chemother,2011,55(6):2968-2970.
[20] Kaiser RM, Castanheira M, Jones RN, et al.Trends in Klebsiella pneumoniae carbapenemase-positive K. pneumoniae in US hospitals: report from the 2007-2009 SENTRY Antimicrobial Surveillance Program[J]. Diagn Microbiol Infect Dis,2013,76(3):356-360.
[21] Deshpande LM, Rhomberg PR, Sader HS, et al.Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States Medical Centers: report from the MYSTIC Program(1999-2005)[J]. Diagn Microbiol Infect Dis,2006,56(4):367-372.
[22] Patel G, Huprikar S, Factor SH, et al.Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies[J]. Infect Control Hosp Epidemiol,2008,29(12):1099-1106.
[23] Qi Y, Wei Z, Ji S, et al.ST11, the dominant clone of KPC-producing Klebsiella pneumoniae in China[J]. J Antimicrob Chemother,2011,66(2):307-312.
[24] Li G, Wei Q, Wang Y, et al.Novel genetic environment of the plasmid-mediated KPC-3 gene detected in Escherichia coli and Citrobacter freundii isolates from China[J]. Eur J Clin Microbiol Infect Dis,2011,30(4):575-580.
[25] Zhang X, Lü X, Zong Z.Enterobacteriaceae producing the KPC-2 carbapenemase from hospital sewage[J]. Diagn Microbiol Infect Dis,2012,73(2):204-206.
[26] Wang D, Hou W, Chen J, et al.Characterization of the blaKPC-2 and blaKPC-3 genes and the novel blaKPC-15 gene in Klebsiella pneumoniae[J]. J Med Microbiol,2014,63(Pt 7):981-987.
[27] Li H, Zhang J, Liu Y, et al. Molecular characteristics of carbapenemase-producing Enterobacteriaceae in China from 2008 to 2011: predominance of KPC-2 enzyme[J]. Diagn Microbiol Infect Dis,2014,78(1):63-65.
[28] Bowers JR, Kitchel B, Driebe EM, et al.Genomic analysis of the emergence and rapid global dissemination of the clonal group 258 Klebsiella pneumoniae Pandemic[J]. PLoS One,2015,10(7):e0133727.
[29] Chiang TT, Yang YS, Yeh KM, et al.Quantification and comparison of virulence and characteristics of different variants of carbapenemase-producing Klebsiella pneumoniae clinical isolates from Taiwan and the United States[J]. J Microbiol Immunol Infect,2016,49(1):83-90.
[30] Yang J, Ye L, Guo L, et al. A nosocomial outbreak of KPC-2-producing Klebsiella pneumoniae in a Chinese hospital: dissemination of ST11 and emergence of ST37, ST392 and ST395[J]. Clin Microbiol Infect,2013 Nov,19(11):E509-E515.
[31] Yu WL, Lee MF, Tang HJ, et al. Emergence of KPC new variants(KPC-16 and KPC-17) andongoing outbreak in southern Taiwan[J]. Clin Microbiol Infect,2015,21(4):347,e5-e8.
[32] Tseng IL, Liu YM, Wang SJ, et al.Emergence of carbapenemase producing Klebsiella Pneumonia and Spread of KPC-2 and KPC-17 in Taiwan: A Nationwide Study from 2011 to 2013[J]. PLoS One,2015,10(9):e0138471.
[33] Kumar V, Sun P, Vamathevan J, et al.Comparative genomics of Klebsiella pneumoniae strains with different antibiotic resistance profiles[J]. Antimicrob Agents Chemo-ther,2011,55(9):4267-4276.
[34] Liu P, Li P, Jiang X, et al.Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain isolated from human sputum[J]. J Bacteriol,2012,194(7):1841-1842.
[35] Deleo FR, Chen L, Porcella SF, et al.Molecular dissection of the evolution of carbapenem-resistant multilocus sequence type 258 Klebsiella pneumoniae[J]. Proc Natl Acad Sci U S A,2014,111(13):4988-4993.
[36] Brisse S, Fevre C, Passet V, et al.Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization[J]. PLoS One,2009,4(3):e4982.
[37] Pitout JD, Nordmann P, Poirel L.Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance[J]. Antimicrob Agents Chemother,2015,59(10):5873-5884.
[38] Chen L, Mathema B, Pitout JD, et al.Epidemic Klebsiella pneumoniae ST258 is a hybrid strain[J]. MBio,2014,5(3):e01355-e01314.
[39] Cuzon G, Naas T, Villegas MV, et al.Wide dissemination of Pseudomonas aeruginosa producing beta-lactamase blaKPC-2 gene in Colombia[J]. Antimicrob Agents Chemo-ther,2011,55(11):5350-5353.
[40] Chen L, Mathema B, Chavda KD, et al.Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding[J]. Trends Microbiol,2014,22(12):686-696.
[41] Naas T, Cuzon G, Villegas MV, et al.Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene[J]. Antimicrob Agents Chemother,2008,52(4):1257-1263.
[42] Cuzon G, Naas T, Nordmann P.Functional characterization of Tn4401, a Tn3-based transposon involved in blaKPC gene mobilization[J]. Antimicrob Agents Chemo-ther,2011,55(11):5370-5373.
[43] Gootz TD, Lescoe MK, Dib-Hajj F, et al.Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital[J]. Antimicrob Agents Chemother,2009,53(5):1998-2004.
[44] Chen L, Chavda KD, Al Laham N, et al.Complete nucleotide sequence of a blaKPC-harboring IncI2 plasmid and its dissemination in New Jersey and New York hospitals[J]. Antimicrob Agents Chemother,2013,57(10):5019-5025.
[45] Chen L, Chavda KD, Melano RG, et al.Comparative genomic analysis of KPC-encoding pKpQIL-like plasmids and their distribution in New Jersey and New York Hospitals[J]. Antimicrob Agents Chemother,2014,58(5):2871-2877.
[46] Chen YT, Lin JC, Fung CP, et al.KPC-2-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan[J]. J Antimicrob Chemother,2014,69(3):628-631.

产KPC型碳青霉烯酶肺炎克雷伯菌流行现状及分子遗传学研究进展

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 7

编辑推荐

Metrics

本文评价

[1]	王明燚, 朱燕. 荧光标记人透明带融合蛋白质粒的构建及其在中国仓鼠卵巢细胞内的表达[J]. 诊断学理论与实践, 2021, 20(06): 557-561.
[2]	蒋晓飞, 周迎. 碳青霉烯耐药肺炎克雷伯菌的耐药与传播机制研究进展及对策[J]. 诊断学理论与实践, 2018, 17(06): 623-629.
[3]	沈平华, 张贤华, 蒋晓飞, 陈慧芬. 肺炎克雷伯菌中携带碳青霉烯酶KPC-2基因的质粒分型[J]. 诊断学理论与实践, 2018, 17(06): 640-644.
[4]	李莉, 王晓, 王尧, 康健, 周罗成, 王海嵘. 血栓调节蛋白表皮生长因子样结构功能域在毕赤酵母中的表达[J]. 诊断学理论与实践, 2017, 16(01): 55-59.
[5]	孙红, 郭普, 钟政荣,. 肺炎克雷伯菌产碳青霉烯酶型碳青霉烯酶的研究进展[J]. 诊断学理论与实践, 2012, 11(05): 528-530.
[6]	徐洪, 胡亮, 倪培华, 吴洁敏, 赵涵芳,. 人regucalcin和红色荧光蛋白融合基因的构建及表达[J]. 诊断学理论与实践, 2006, 5(03): 225-229.
[7]	王海嵘, 顾春红, 钟济华, 王婷, 韩洁英, 陈芳源, 欧阳仁荣,. 流式细胞术结合G418筛选重组质粒稳定转染细胞[J]. 诊断学理论与实践, 2006, 5(01): 52-55.