Abstract: Objective: To study the value of ultrasound-guided fine-needle aspiration biopsy(US-FNAB) and thyroid ultrasound imaging reporting and data system(TI-RADS) in the diagnosis of thyroid nodules. Methods: Data from 2 901 patients undergone thyroid ultrasound guided fine needle aspiration biopsy at Ruijin Hospital during January 2017 to June 2017 were retrospectively reviewed, and the cytologic findings were contrasted with the results of TI-RADS classification. Results: According to the results of cytological diagnosis, thyroid benign nodules were more commonly seen in TI-RADS 3 and 4A and accounting for 94.00% and 61.62%, respectively; while malignant nodules were commonly seen in TI-RADS 4A, 4B, 4C, and 5 and accounting for 38.38%, 78.34%, 87.02% and 92.87%, respectively. Conclusions: It is recommended that when one or more of the indicators in ultrasound TI-RADS classification suggests a malignant nodule(≥4A), US-FNAB is required to identify the character of the nodule. US-FNAB combined with TI-RADS classification can be used in the differential diagnosis of thyroid nodules and has importantclinical significance for preoperative diagnosis.

Key words: Thyroid nodule, Fine-needle aspiration biopsy, Thyroid imaging reporting and data system