Journal of Diagnostics Concepts & Practice ›› 2018, Vol. 17 ›› Issue (01): 98-101.doi: 10.16150/j.1671-2870.2018.01.018

• Original articles • Previous Articles     Next Articles

Correlation between sperm DNA fragmentation index and sperm morphology

LIU Yiping1, TANG Yuanyuan1,2, XU Kui1,2, TENG Xiaoming2   

  1. 1. Department of Graduate Education, Weifang Medical University, School of clinical medicine, Shandong Weifang 261042, China;
    2. Center for Assisted Reproductive Medicine, First Maternity and Infant Hospital Affiliated to Tongji University, Shanghai 200040, China
  • Received:2017-09-18 Published:2018-02-25

Abstract: Objective: To study the correlation between sperm DNA fragmentation index (DFI) and sperm morphology in male semen. Methods: A total of 3 068 male subjects were enrolled and their semen samples were obtained and analyzed. According to the sperm DFI, the semen samples were divided into three groups: DFI<15%, 15%-30%, >30%. According to the percentage of spermatocytes with normal morphology, the sperm were divided into three groups: <4%, 4%-10%, > 10%. The relationship between DNA fragment index and sperm morphology in these groups was analyzed. Results: There was no significant difference in rates of normal morphology, head deformity and mixed deformity between groups with different sperm DFI index(P>0.05). There was no significant difference in sperm DFI between groups with different percen-tage of normal morphology of sperm. There was no significant correlation between different sperm normal morphology group and sperm DFI group(P>0.05). Conclusions: This study showed that there is no correlation between sperm DFI and sperm morphology.

Key words: The sperm DNA fragmentation index, Sperm morphology, Male infertility, Correlation

CLC Number: