Journal of Diagnostics Concepts & Practice ›› 2019, Vol. 18 ›› Issue (06): 649-654.doi: 10.16150/j.1671-2870.2019.06.009
• Original articles • Previous Articles Next Articles
XU Haimin1, CHEN Xiaoyan1(), ZHANG Jing2, WANG Chaofu1
Received:
2019-08-01
Online:
2019-12-25
Published:
2019-12-25
Contact:
CHEN Xiaoyan
E-mail:cxy11832@rjh.com.cn
CLC Number:
XU Haimin, CHEN Xiaoyan, ZHANG Jing, WANG Chaofu. Pulmonary colloid adenocarcinoma: Clinical pathological analysis of 4 cases and review of literature[J]. Journal of Diagnostics Concepts & Practice, 2019, 18(06): 649-654.
病例 | 性别 | 年龄 (岁) | 吸烟 史 | 症状 | 体积(cm) | PET/CT | 部位 | 手术方式 | 病理分期 | 随访 |
---|---|---|---|---|---|---|---|---|---|---|
1 | 男 | 61 | 无 | 体检发现,无症状 | 1.6×1.6 ×1.5 | 代谢轻度增高 | 右肺上叶 | 肺段切除+纵隔 淋巴结清除 | ⅢA (T1bN2M0) | 术后34个月无复发及远处转移 |
2 | 男 | 67 | 有 | 咳嗽、咳痰,胸闷、气促 | 2.9×1.7 ×1.5 | 未查 | 右肺下叶 | 肺叶切除+纵隔 淋巴结清除 | ⅠA3 (T1cN0M0) | 术后半年发生骨转移及脑转移 |
3 | 男 | 66 | 有 | 体检发现,无症状 | 1.6×1.0 ×1.0 | 未查 | 右肺上叶 | 肺叶切除+纵隔 淋巴结清除 | ⅠA2 (T1bN0M0) | 术后31个月无 复发转移 |
4 | 男 | 62 | 有 | 全身乏力半年余 | 12.0×11.0 ×8.0 | 代谢轻度增高 | 右肺上叶 | 肺叶切除+纵隔 淋巴结清除 | ⅢA (T4N0M0) | 术后半年因肺部感染、呼吸衰竭死亡 |
[1] | Travis WD, Brambilla E, Burke AP, et al. WHO Classification oftumours of the lung, pleura, thymus and heart[M]. Lyon: IARC Press, 2015:40-41. |
[2] |
Zenali MJ, Weissferdt A, Solis LM, et al. An update on clinicopathological, immunohistochemical, and molecular profiles of colloid carcinoma of the lung[J]. Hum Pathol, 2015, 46(6): 836-842.
doi: 10.1016/j.humpath.2014.10.032 URL |
[3] |
Sonzogni A, Bianchi F, Fabbri A, et al. Pulmonary adenocarcinoma with mucin production modulates phenotype according to common genetic traits: a reappraisal of mucinous adenocarcinoma and colloid adenocarcinoma[J]. J Pathol Clin Res, 2017, 3(2):139-152.
doi: 10.1002/cjp2.67 URL |
[4] |
Cha YJ, Shim HS, Han J, et al. Clinicopathologic ana-lysis of 10 cases of pulmonary colloid adenocarcinoma and prognostic implication of invasive micropapillary component[J]. Pathol Res Pract, 2018, 214(12):2093-2098.
doi: 10.1016/j.prp.2018.10.014 URL |
[5] | Masai K, Sakurai H, Suzuki S, et al. Clinicopathological features of colloid adenocarcinoma of the lung: A report of six cases[J]. JSurg Oncol, 2016, 114(2):211-215. |
[6] |
Rossi G, Murer B, Cavazza A, et al. Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special refe-rence to CDX-2 homeobox gene and MUC2 expression[J]. Am J Surg Pathol, 2004, 28(4):442-452.
doi: 10.1097/00000478-200404000-00003 URL |
[7] |
Graeme-Cook F, Mark EJ. Pulmonary mucinous cystic tumors of borderline malignancy[J]. Hum Pathol, 1991, 22(2):185-190.
pmid: 2001880 |
[8] | Moran CA, Hochholzer L, Fishback N, et al. Mucinous (so-called colloid) carcinomas of lung[J]. Mod Pathol, 1992, 5(6): 634-638. |
[9] |
Gao ZH, Urbanski S J. The spectrum of pulmonary mu-cinous cystic neoplasia : a clinicopathologic and immunohistochemical study of ten cases and review of litera-ture[J]. Am J Clin Pathol, 2005, 124(1):62-70.
doi: 10.1309/52XXR6E6U0J2JX0F URL |
[10] |
Berger K L, Nicholson S A, Dehdashti F, et al. FDG PET evaluation of mucinous neoplasms: correlation of FDG uptake with histopathologic features[J]. Am J Roentgenol, 2000, 174(4):1005-1008.
pmid: 10749239 |
[11] |
Shim S S, Han J. FDG-PET/CT imaging in assessing mucin-producing non-small cell lung cancer with pathologic correlation[J]. Ann Nucl Med, 2010, 24(5):357-362.
doi: 10.1007/s12149-010-0358-x URL |
[12] | Miyake A, Okudela K, Matsumura M, et al. Update on the potential significance of psammoma bodies in lung adenocarcinoma from a modern perspective[J]. Histopatho-logy, 2018, 72(4):609-618. |
[13] |
Chang JC, Montecalvo J, Borsu L, et al. Bronchiolar adenoma: expansion of the concept of ciliated mucono-dular papillary tumors with proposal for revised terminology based on morphologic, immunophenotypic, and genomic analysis of 25 cases[J]. Am J Surg Pathol, 2018, 42(8):1010-1026.
doi: 10.1097/PAS.0000000000001086 URL |
[14] |
Chuang H W, Liao J B, Chang H C, et al. Ciliated muconodular papillary tumor of the lung: a newly defined peripheral pulmonary tumor with conspicuous mucin pool mimicking colloid adenocarcinoma: a case report and review of literature[J]. Pathol Int, 2014, 64(7):352-357.
doi: 10.1111/pin.12179 URL |
[15] | 陈晓炎, 杨晓群, 袁菲, 等. 肺纤毛黏液结节性乳头状肿瘤2例临床病理分析及文献复习[J]. 诊断学理论与实践, 2018, 17(5):575-580. |
[16] |
Ye J, Findeis-Hosey JJ, Yang Q, et al. Combination of napsin A and TTF-1 immunohistochemistry helps in differentiating primary lung adenocarcinoma from metastatic carcinoma in the lung[J]. Appl Immunohistochem Mol Morphol, 2011, 19(4):313-317.
doi: 10.1097/PAI.0b013e318205b059 URL |
[17] |
Rossi G, Cavazza A, Righi L, et al. Napsin-A, TTF-1, EGFR, and ALK status determination in lung primary and metastatic mucin-producing adenocarcinomas[J]. Int J Surg Pathol, 2014, 22(5):401-407.
doi: 10.1177/1066896914527609 URL |
[18] |
Kalhor N. Colloid carcinoma of the lung: Current views[J]. Semin Diagn Pathol, 2014, 31(4):265-270.
doi: 10.1053/j.semdp.2014.06.003 pmid: 25239272 |
[19] | Morita K, Nagashima A, Takemoto N, et al. Primary pulmonary mucinous (colloid) adenocarcinoma with postope-rative bone metastasis[J]. Ann Thorac Cardiovas Surg, 2014, 20(Suppl):677-681. |
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