Analysis of lymph node density related clinical and gray-scale sonographic characteristics of papillary thyroid carcinoma

doi:10.16150/j.1671-2870.2019.05.013

Abstract

Abstract:

Objective: To investigate the correlation of clinical and gray-scale sonographic features with cervical lymph node density (LND in papillary thyroid carcinoma(PTC). Methods: A total of 148 patients with PTC were divided into 2 groups: LND≤0.19 and LND>0.19. Clinical data of patients(age, gender and Hashimoto thyroiditis) were collected. Number of PTC nodules as well as the size, margin, internal architecture, internal echoes, calcification and contacting with thyroid capsule were evaluated by gray-scale sonography. Single factor analysis and logistic regression analysis were used to evaluate the correlation between the clinical data and LND. Results: Single factor analysis showed that age,number of nodule, size, calcification and contacting with thyroid capsule were correlated with LND. Logistic regression analysis showed that LND was correlated with the nodule size, calcification and contacting with thyroid capsule. Conclusions: Gray-scale sonographic features may indicate the LND level in PTC, which may be helpful for formulating treatment plan to reduce the risk of recurrence and improving survival.

Key words: Papillary thyroid carcinoma, Lymph node density, Gray-scale sonography

CLC Number:

R736.1

YU Xiaoqing, ZHAN Weiwei, ZHOU Wei, WU Yu, WANG Yi, LI Weiwei, TAO Lingling, FAN Jinfang. Analysis of lymph node density related clinical and gray-scale sonographic characteristics of papillary thyroid carcinoma[J]. Journal of Diagnostics Concepts & Practice, 2019, 18(05): 555-559.

Figures/Tables 5

References 20

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因素	LND≤0.19	LND>0.19	合计	χ²值	P值
性别				0.895	0.344
男	63	52	115
女	15	18	38
年龄				7.271	0.007
45岁	34	46	80
≥45岁	44	24	68
伴桥本甲状腺炎				2.611	0.106
是	26	15	41
否	52	55	107

甲状腺癌结节	LND≤0.19	LND>0.19	合计	χ²值	P值
纵横比				1.340	0.247
<1	24	46	70
≥1	34	44	78
回声水平				1.267	0.260
非低回声	11	11	22
低回声	47	79	126
内部结构				0.380	0.538
实性为主	3	7	10
实性	55	83	138
数目				4.079	0.043
单灶	48	61	109
多灶	10	29	39
不规则	45	70	115	0.001	0.978
结节钙化				9.967	0.002
无	23	15	38
有	35	75	110
与被膜接触				18.338	<0.001
否	36	24	60
是	22	66	88
结节最大径（cm）				22.25	<0.001
<1	50	20	70
1~2 cm	22	34	56
2~<3 cm	6	10	16

甲状腺癌结节	B	S.E.	Wald	df	Sig.	Exp(B)
结节数目	1.184	0.523	0.113	1	0.129	1.266
结节最大径	1.206	0.443	7.410	1	0.006	3.340
结节纵横比	0.749	0.572	1.711	1	0.838	1.115
结节钙化	1.378	0.480	8.255	1	0.004	3.967
边界与被膜接触	0.836	0.420	3.954	1	0.047	2.306