Journal of Diagnostics Concepts & Practice >

2019 , Vol. 18 >Issue 06: 676 - 679

DOI: https://doi.org/10.16150/j.1671-2870.2019.06.014

Original articles

Experimental evaluation of efficacy of a HIV filter

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  • Department of Infectious Immunity, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China

Received date: 2019-10-10

  Online published: 2019-12-25

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Abstract

Objective: To test the efficacy of a disposable membrane filter for the elimination of HIV. Methods: A total of 10 plasma samples were tested in this study. Plasma samples containing HIV were pressurizedly filtered through the filter. Copies of HIV RNA in the plasma before and after filtration were counted to calculate the efficacy of the filter. Results: The average HIV clearance rate of the filter was 96.62%. There was significant difference in number of HIV RNA copies before and after filtration (P=0.001). However, linear relationship was not seen between the clearance rate and the initial number of HIV RNA copies (P=0.924 2). Conclusions: The HIV clearance rate of this disposable membrane filter is high, and it might be feasible to eliminate the HIV virus by physical adsorption.

Key words： Human immunodeficiency virus; Filtration membrane; Clearance rate

Cite this article

ZHANG Lin, ZHOU Ying, LI Haicong, SUN Meiyan, SUN Wenxiu, LU Lingqing, ZHU Zhaoqin, TANG Qi, ZHANG Renfang, SHEN Yinzhong, LU Hongzhou . Experimental evaluation of efficacy of a HIV filter[J]. Journal of Diagnostics Concepts & Practice, 2019 , 18(06) : 676 -679 . DOI: 10.16150/j.1671-2870.2019.06.014

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