Journal of Diagnostics Concepts & Practice >

2019 , Vol. 18 >Issue 05: 543 - 547

DOI: https://doi.org/10.16150/j.1671-2870.2019.05.011

Original articles

Research on acoustic radiation force impulse imaging in quantitative assessment of testicular stiffness in non-sterility varicocele patients

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  • Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Received date: 2018-05-15

  Online published: 2019-10-25

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Abstract

Objective: To investigate the correlation between the change of testicular tissue stiffness and the semen quality of non-sterility left varicocele(VC) patients by using acoustic radiation force impulse imaging(ARFI). Methods: According to the results of palpation and ultrasonic examination,143 cases of non-sterility left varicocele(VC) patients were divided into subclinical varicocele(SVC) group(42 cases), grade VC1 group (33 cases), grade VC2 group (49 cases),grade VC3 group (19 cases); in addition, 67 cases of normal subjects were served as controls.All subjects underwent semen examination and routine ultrasound examination. The shear wave velocity (SWV) in testis of all subjects were determined by acoustic pulse radiation imaging. The rank-sum test was used to compare the difference of SWV values and sperm quality between VC groups and control group. Pearson correlation analysis was used to analyze the correlation between sperm density, testicular volume, internal diameter of varicose veins and SWV in VC patients. Results: Compared with the control group, SWV value of testis decreased in VC group and VC2, VC3 group(Zvc-CG=-5.015, Zvc2-CG=-7.841, Zvc3-CG=-6.182, P<0.01), sperm density decreased in the VC group and VC2, VC3 groups(Zvc-CG=-6.878,Zvc2-CG=-8.258,Zvc3-XG=-8.695, P<0.01). Compared with the SVC group, SWV value of testis decreased in VC2, VC3 groups (Zvc2-svc=6.674, Zvc3-svc=5.557, P<0.01), sperm density decreased in VC2, VC3 group(Zvc2-svc=6.407, Zvc3-svc=7.432, P<0.01). Compared with VC1 group, SWV value of testis decreased in VC2, VC3 groups (Zvc2-vc1=6.480, Zvc3-vc1=5.529, P<0.01), sperm density in VC2, VC3 groups also decreased (Zvc2-vc1=4.471, Zvc3-vc1=5.953, P<0.01). Pearson correlation analysis showed that there was a positive correlation between SWV value and sperm density and testicular volume in VC group（rleft=0.732,rright=0.664, P<0.01; rleft=0.595,rright=0.417, P<0.01）. And there was a negative correlation between SWV value and internal diameter of spermatic vein（rleft=-0.758, rright=-0.775, P<0.01）. Conclusions: The SWV value of testis can be used as a reference index to evaluate the change of testicular tissue stiffness and testicular spermatogenesis in VC patients.

Key words： Varicocele; Acoustic radation force impulse imaging; Shear wave velocity; Testis volume; Semen quality

Cite this article

LI Min, LIU Jun, WANG Zhiqian, ZHAN Weiwei . Research on acoustic radiation force impulse imaging in quantitative assessment of testicular stiffness in non-sterility varicocele patients[J]. Journal of Diagnostics Concepts & Practice, 2019 , 18(05) : 543 -547 . DOI: 10.16150/j.1671-2870.2019.05.011

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