内科理论与实践 ›› 2021, Vol. 16 ›› Issue (06): 431-434.doi: 10.16138/j.1673-6087.2021.06.013
收稿日期:
2021-05-27
出版日期:
2021-12-27
发布日期:
2022-07-25
通讯作者:
刘超
E-mail:liuchao@nfmcn.com
Received:
2021-05-27
Online:
2021-12-27
Published:
2022-07-25
中图分类号:
朱宋达, 陈国芳, 徐书杭, 刘超. 替妥木单抗:Graves眼病的新希望[J]. 内科理论与实践, 2021, 16(06): 431-434.
[1] |
Bartalena L, Piantanida E, Gallo D, et al. Epidemiology, natural history, risk factors, and prevention of Graves’ orbitopathy[J]. Front Endocrinol (Lausanne), 2020, 11: 615993.
doi: 10.3389/fendo.2020.615993 URL |
[2] |
Hodgson NM, Rajaii F. Current understanding of the progression and management of thyroid associated orbitopathy[J]. Ophthalmol Ther, 2020, 9(1): 21-33.
doi: 10.1007/s40123-019-00226-9 URL |
[3] |
Bartalena L, Baldeschi L, Dickinson AJ, et al. Consensus statement of the European group on Graves’ orbitopathy (EUGOGO) on management of Graves’ orbitopathy[J]. Thyroid, 2008, 18(3): 333-346.
doi: 10.1089/thy.2007.0315 pmid: 18341379 |
[4] |
Bartalena L, Baldeschi L, Boboridis K, et al. The 2016 European Thyroid Association/European Group on Graves’ orbitopathy guidelines for the management of Graves’ orbitopathy[J]. Eur Thyroid J, 2016, 5(1): 9-26.
doi: 10.1159/000443828 pmid: 27099835 |
[5] | Nicosia L, Reverberi C, Agolli L, et al. Orbital radiotherapy plus concomitant steroids in moderate-to-severe Graves’ ophthalmopathy[J]. Int J Endocrinol Metab, 2019, 17(1): e84427. |
[6] |
Aktaran S, Akarsu E, Erbaigci I, et al. Comparison of intravenous methylprednisolone therapy vs. oral methylprednisolone therapy in patients with Graves’ ophthalmopathy[J]. Int J Clin Pract, 2007, 61(1): 45-51.
pmid: 16889639 |
[7] |
Kotwal A, Stan M. Current and future treatments for Graves’ disease and Graves’ ophthalmopathy[J]. Horm Metab Res, 2018, 50(12): 871-886.
doi: 10.1055/a-0739-8134 URL |
[8] |
Stan MN, Garrity JA, Carranza Leon BG, et al. Randomized controlled trial of rituximab in patients with Graves’ orbitopathy[J]. J Clin Endocrinol Metab, 2015, 100(2): 432-441.
doi: 10.1210/jc.2014-2572 URL |
[9] |
Salvi M, Vannucchi G, Currò N, et al. Efficacy of B-cell targeted therapy with rituximab in patients with active moderate to severe Graves’ orbitopathy[J]. J Clin Endocrinol Metab, 2015, 100(2): 422-431.
doi: 10.1210/jc.2014-3014 URL |
[10] |
Stan MN, Salvi M. Mangement of endocrine disease: rituximab therapy for Graves’ orbitopathy[J]. Eur J Endocrinol, 2017, 176(2): R101-R109.
doi: 10.1530/EJE-16-0552 URL |
[11] |
Perez-Moreiras JV, Gomez-Reino JJ, Maneiro JR, et al. Efficacy of tocilizumab in patients with moderate-to-severe corticosteroid-resistant Graves orbitopathy[J]. Am J Ophthalmol, 2018, 195: 181-190.
doi: S0002-9394(18)30431-8 pmid: 30081019 |
[12] | Rivera-Grana E, Lin P, Suhler EB, et al. Methotrexate as a corticosteroid-sparing agent for thyroid eye disease[J]. J Clin Exp Ophthalmol, 2015, 6(2): 422. |
[13] |
Taylor PN, Zhang L, Lee RWJ, et al. New insights into the pathogenesis and nonsurgical management of Graves orbitopathy[J]. Nat Rev Endocrinol, 2020, 16(2): 104-116.
doi: 10.1038/s41574-019-0305-4 pmid: 31889140 |
[14] |
Ju Y, Yang J. Teprotumumab for the treatment of thyroid eye disease[J]. Expert Rev Clin Immunol, 2020, 16(8): 739-743.
doi: 10.1080/1744666X.2020.1801421 URL |
[15] |
Rapoport B, McLachlan SM. Reflections on thyroid autoimmunity[J]. Horm Metab Res, 2018, 50(12): 840-852.
doi: 10.1055/a-0725-9297 pmid: 30357776 |
[16] | Tabasum A, Khan I, Taylor P, et al. Thyroid antibody-negative euthyroid Graves’ ophthalmopathy[J]. Endocrinol Diabetes Metab Case Rep, 2016, 2016: 160008. |
[17] |
Pritchard J, Han R, Horst N, et al. Immunoglobulin activation of T cell chemoattractant expression in fibroblasts from patients with Graves’ disease is mediated through the insulin-like growth factor I receptor pathway[J]. J Immunol, 2003, 170(12): 6348-6354.
pmid: 12794168 |
[18] | 张荧钗, 徐书杭, 刘超. 胰岛素样生长因子Ⅰ受体及其在Graves眼病中作用研究进展[J]. 中华内分泌代谢杂志, 2020, 36(9): 799-802. |
[19] | Łacheta D, Miéskiewicz P, Głuszko A, et al. Immunological aspects of Graves’ ophthalmopathy[J]. Biomed Res Int, 2019, 2019: 7453260. |
[20] |
Smith TJ. Thyroid-associated ophthalmopathy: emergence of teprotumumab as a promising medical therapy[J]. Best Pract Res Clin Endocrinol Metab, 2020, 34(1): 101383.
doi: 10.1016/j.beem.2020.101383 URL |
[21] |
Patel A, Yang H, Douglas RS. A new era in the treatment of thyroid eye disease[J]. Am J Ophthalmol, 2019, 208: 281-288.
doi: S0002-9394(19)30382-4 pmid: 31377284 |
[22] |
Krieger CC, Neumann S, Gershengorn MC. Is there evidence for IGF1R-stimulating abs in Graves’ orbitopathy pathogenesis?[J]. Int J Mol Sci, 2020, 21(18): 6561.
doi: 10.3390/ijms21186561 URL |
[23] |
Krieger CC, Boutin A, Jang D, et al. Arrestin-β-1 physically scaffolds TSH and IGF1 receptors to enable crosstalk[J]. Endocrinology, 2019, 160(6): 1468-1479.
doi: 10.1210/en.2019-00055 URL |
[24] |
Paik JS, Kim SE, Kim JH, et al. Insulin-like growth factor-1 enhances the expression of functional TSH receptor in orbital fibroblasts from thyroid-associated ophthalmopathy[J]. Immunobiology, 2020, 225(2): 151902.
doi: 10.1016/j.imbio.2019.151902 URL |
[25] |
Ju Y, Yang J. Teprotumumab for the treatment of thyroid eye disease[J]. Expert Rev Clin Immunol, 2020, 16(8): 739-743.
doi: 10.1080/1744666X.2020.1801421 URL |
[26] |
Ali F, Chorsiya A, Anjum V, et al. Teprotumumab (tepezza): from the discovery and development of medicines to USFDA approval for active thyroid eye disease (TED) treatment[J]. Int Ophthalmol, 2021, 41(4): 1549-1561.
doi: 10.1007/s10792-021-01706-3 URL |
[27] |
Terwee CB, Gerding MN, Dekker FW, et al. Development of a disease specific quality of life questionnaire for patients with Graves’ ophthalmopathy[J]. Br J Ophthalmol, 1998, 82(7): 773-779.
doi: 10.1136/bjo.82.7.773 URL |
[28] |
Smith TJ, Kahaly GJ, Ezra DG, et al. Teprotumumab for thyroid-associated ophthalmopathy[J]. N Engl J Med, 2017, 376(18): 1748-1761.
doi: 10.1056/NEJMoa1614949 URL |
[29] |
Winn BJ, Kersten RC. Teprotumumab: interpreting the clinical trials in the context of thyroid eye disease pathogenesis and current therapies[J]. Ophthalmology, 2021, 128(11): 1627-1651.
doi: 10.1016/j.ophtha.2021.04.024 URL |
[30] |
Douglas RS, Kahaly GJ, Patel A, et al. Teprotumumab for the treatment of active thyroid eye disease[J]. N Engl J Med, 2020, 382(4): 341-352.
doi: 10.1056/NEJMoa1910434 URL |
[31] |
Mishra S, Maurya VK, Kumar S, et al. Clinical management and therapeutic strategies for the thyroid-associated ophthalmopathy[J]. Curr Eye Res, 2020, 45(11): 1325-1341.
doi: 10.1080/02713683.2020.1776331 URL |
[1] | 欧阳火牛,吴祎炜,程志华,郭智霖. 颅眶神经纤维瘤病致蝶骨翼发育不良的手术治疗[J]. 组织工程与重建外科杂志, 2018, 14(3): 136-142. |
[2] | 张倩为, 王曙,. 眶成纤维细胞在Graves眼病发病中的作用[J]. 内科理论与实践, 2012, 7(06): 464-467. |
[3] | 曹明明, 童南伟,. Graves眼病的诊断和治疗[J]. 内科理论与实践, 2010, 5(02): 177-179. |
[4] | 王坚, 叶小珍,. 糖尿病合并Graves眼病者需慎用过氧化物酶体增殖物激活受体γ激动剂[J]. 内科理论与实践, 2008, 3(05): 332-334. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||