Effect of dizocine application combined with propofol in laparoscopic hepatectomy

doi:10.16139/j.1007-9610.2020.01.016

Abstract

CLC Number:

R614
R735.7

SU Meiru, FENG Yanping, ZHAO Yingjie. Effect of dizocine application combined with propofol in laparoscopic hepatectomy[J]. Journal of Surgery Concepts & Practice, 2020, 25(01): 74-76.

Figures/Tables 5

References 15

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项目	A组（n=60）	B组（n=60）	t/χ²	P值
年龄（岁）	56.4±8.6	55.3±10.0	0.646	0.520
男/女	35/25	31/29	0.539	0.463
BMI	22.8±2.2	23.0±2.5	-0.465	0.643
ASA分级			0.586	0.444
Ⅰ	41	37
Ⅱ	19	23
手术时间（min）	194.2±23.0	189.0±25.2	1.181	0.240
HBV感染阳性	50	45	1.263	0.261
TNM分期			0.821	0.663
Ⅰ	15	19
Ⅱ	30	29
Ⅲ	15	12
肿瘤最大径（cm）	4.80±1.29	5.01±1.44	-0.841	0.402
病灶数≥2个	23	20	0.326	0.568

指标	组别	T0	T1	T2	T3	T4
心率（次/min）	A组	77.3±8.9	68.5±7.0	71.0±6.8^a)	74.2±7.8^a)	75.1±8.0
	B组	76.8±8.3	67.6±8.8	65.0±7.2	68.9±8.2	74.0±9.2
	F值	F组间=4.927、F时间=13.008、F交互=7.751
	P值	P组间=0.001、P时间=0.000、P交互=0.000
平均动脉压（mmHg）	A组	95.8±7.8	88.2±6.6^a)	90.0±7.4^a)	90.9±7.1^a)	94.5±6.5
	B组	96.3±6.5	82.5±7.3	84.3±8.2	85.1±6.4	95.2±7.2
	F值	F组间=6.236、F时间=11.446、F交互=8.239
	P值	P组间<0.001、P时间<0.001、P交互<0.001

组别	n	T0	T1	T2	T3	T4
A组	60	94.9±2.3	48.0±2.2	52.1±4.2^a)	53.6±2.3^a)	53.2±1.9^a)
B组	60	95.2±2.5	47.3±2.6	49.1±1.4	49.3±1.8	48.5±2.0
F值		F组间=7.003、F时间=59.381、F交互=11.381
P值		P组间<0.001、P时间<0.001、P交互<0.001

组别	n	MMP2（ng/L）		MMP9（ng/L）
组别	n	术前	术后12 h	术前	术后12 h
A组	60	314.8±19.6	340.2±21.3	344.8±15.7	360.2±18.0
B组	60	312.0±18.1	355.8±23.4	340.0±16.2	374.5±21.3
t值		0.813	-3.819	1.648	-3.972
P值		0.418	<0.001	0.102	<0.001
组别	n	一氧化氮（μmol/L）		ET-1（μmol/L）
组别	n	术前	术后12 h	术前	术后12 h
A组	60	38.2±5.8	25.1±4.2	122.7±22.0	156.7±25.4
B组	60	39.0±7.1	20.8±5.7	119.4±24.2	183.0±30.6
t值		-0.676	4.704	0.782	-5.123
P值		0.500	<0.001	0.436	<0.001

组别	n	嗜睡	恶心呕吐	头昏	不良反应发生率[n（%）]
A组	60	1	1	2	4（6.67）
B组	60	3	2	3	8（13.33）
χ²值					1.481
P值					0.224

Effect of dizocine application combined with propofol in laparoscopic hepatectomy

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