Journal of Surgery Concepts & Practice ›› 2025, Vol. 30 ›› Issue (2): 106-111.doi: 10.16139/j.1007-9610.2025.02.03

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Controversial points in the surgical treatment of gallbladder cancer with delayed diagnoses

LE Sen1, ZUO Yue1, DENG Zhengdong2(), WANG Jianming2()   

  1. 1. Tianyou Hospital,Wuhan University of Science and Technology,Hubei Wuhan 430064,China
    2. Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Wuhan 430030, China
  • Received:2025-01-29 Online:2025-03-25 Published:2025-07-07
  • Contact: DENG Zhengdong, WANG Jianming E-mail:dengzhengdong0915@163.com;wjm18jgm@aliyun.com

Abstract:

Gallbladder cancer with delayed diagnoses, as a malignant tumor diagnosed intraoperatively or postoperatively incidentally in benign gallbladder diseases, radical surgical treatment is its core treatment, and the necessity of re-operation, timing of surgery, choice of surgical procedure, definition of resection extent, and preoperative neoadjuvant therapy still remain controversial. Re-operation for gallbladder cancer with delayed diagnoses needs to balance tumor radicalization, postoperative risk, and survival benefit, and combining neoadjuvant therapy to facilitate radical treatment, and develop individualized protocols. The multidisciplinary team should integrate innovative technologies and multi-center prospective studies to promote the development of precise treatment strategies for gallbladder cancer with delayed diagnoses and optimize the survival of patients.

Key words: Gallbladder cancer with delayed diagnoses, Radical surgery, Laparoscopic surgery, Neoadjuvant therapy

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