Abstract: Objective To analyze the current incidence and mortality of female breast cancer in Shanghai during the period 2002-2015 and to provide the reference for research on breast cancer prevention and control. Methods The data of female cases with breast cancer were collected by the Shanghai Cancer Registry. The incidence and mortality of female breast cancer in Shanghai between 2013 and 2015 were compared with those in international study in 2018. The age distribution, basis of diagnosis, pathological classification and diagnostic stage were studied. Both standardized rates and age-specific rates of incidence and mortality of breast cancer between 2002 and 2015 were analyzed. Results Breast cancer incidence lists the first rank and the mortality of breast cancer lists the 4th rank in female cancer in Shanghai between 2013 and 2015. Averagely, 5 293 female cases with breast cancer were diagnosed each year between 2013 and 2015 in Shanghai which accounted for 15.82% of total female cancer. The crude rate of incidence was 73.34 per 100 000 and standar-dized rate was 38.45 per 100 000 with ratio of mortality-incidence 0.27. There were 1 448 cases of death due to breast cancer each year accounting for 9.51% of all female cancer death. The crude rate of mortality was 20.06 per 100 000 with standardized rate 7.42 per 100 000. The crude rate of incidence and mortality in Shanghai were higher than that in the world, Eastern Asia, China but lower than in USA. Standardized mortality of breast cancer in Shanghai, however, was lower than that in all including Eastern Asia, USA, China and the world. The age-specific incidences of breast cancer increased with age from 20 to 59 years old with similar incidence in the groups between 55 to 74 years old, and decreased with age increasing from 75 years old. The age-specific mortality increased with age from 20 to 85 years and older. There were 94.39% of new cases of breast cancer with pathological diagnosis, 29.42% of cases on stage one and 30.82% of cases with incomplete data. Between 2002 and 2015, the age-standardized incidence of female breast cancer in Shanghai showed the trend increasing constantly and the trend of mortality without change. Conclusions The age-standardized incidence of female breast cancer increased in Shanghai between 2002 and 2015. The mortality of breast cancer without change suggests effective treatment and improvement of survival.

Key words: Female, Breast Cancer, Incidence, Mortality, Epidemiology