Journal of Surgery Concepts & Practice ›› 2020, Vol. 25 ›› Issue (04): 326-330.doi: 10.16139/j.1007-9610.2020.04.012
• Original article • Previous Articles Next Articles
WU Jingyia, LI Guojingb, FEI Jianc()
Received:
2019-11-08
Online:
2020-07-25
Published:
2022-07-18
Contact:
FEI Jian
E-mail:feijian@hotmail.com
CLC Number:
WU Jingyi, LI Guojing, FEI Jian. Acute pancreatitis as first episode of pancreatic cancer: a report of 17 cases[J]. Journal of Surgery Concepts & Practice, 2020, 25(04): 326-330.
项目 | 例数(%) |
---|---|
血清学检查 | |
肿瘤标志物(CA199、CA125、CEA、 CA242、CA724)任意一项升高 | 13(76.5) |
血淀粉酶升高 | 10(58.8) |
空腹血糖升高 | 9(52.9) |
肝酶(ALT、AST、γ-GT、AKP)任意一项升高 | 6(35.3) |
总胆红素升高 | 4(23.5) |
影像学检查 | |
胰头占位 | 11(64.7) |
胰体尾占位 | 6(35.3) |
胰管扩张 | 15(88.2) |
胆管扩张 | 8(47.1) |
胰管截断 | 5(29.4) |
阻塞性胰腺炎a) | 5(29.4) |
胰源性门静脉高压 | 2(11.8) |
胰尾部萎缩 | 2(11.8) |
血管侵犯(包括腹腔干、肠系膜上下血管、 腹腔动脉主干等) | 7(41.2) |
腹水 | 3(17.6) |
[1] |
Siegel RL, Miller KD, Jemal A. Cancer statistics,2018[J]. CA Cancer J Clin, 2018, 68(1):7-30.
doi: 10.3322/caac.21442 URL |
[2] |
Kamisawa T, Wood LD, Itoi T, et al. Pancreatic cancer[J]. Lancet, 2016, 388(10039):73-85.
doi: 10.1016/S0140-6736(16)00141-0 pmid: 26830752 |
[3] |
Mujica VR, Barkin JS, Go VL. Acute pancreatitis secon-dary to pancreatic carcinoma. Study Group Participants[J]. Pancreas, 2000, 21(4):329-332.
doi: 10.1097/00006676-200011000-00001 URL |
[4] | 王春友, 李非, 赵玉沛, 等. 急性胰腺炎诊治指南(2014)[J]. 临床外科杂志, 2015, 23(1):1-4. |
[5] | 虞先濬, 刘亮, 徐华祥, 等. 胰腺癌综合诊治指南(2018 版)[J]. 临床肝胆病杂志, 2018, 34(10):2109-2120. |
[6] |
Munigala S, Kanwal F, Xian H, et al. Increased risk of pancreatic adenocarcinoma after acute pancreatitis[J]. Clin Gastroenterol Hepatol, 2014, 12(7):1143-1150.e1.
doi: 10.1016/j.cgh.2013.12.033 URL |
[7] |
Imamura M, Asahi S, Yamauchi H, et al. Minute pancrea-tic carcinoma with initial symptom of acute pancreatitis[J]. J Hepatobiliary Pancreat Surg, 2002, 9(5):632-636.
doi: 10.1007/s005340200086 URL |
[8] | 张慧敏, 金梦, 钱家鸣, 等. 胰腺癌合并急性胰腺炎和单纯急性胰腺炎诊断分析[J]. 中国实用内科杂志, 2017, 37(2):145-147. |
[9] | 田雨霖, 郭克建. 慢性胰腺炎与胰腺癌[J]. 中国实用外科杂志, 1997, 17(4):16-17. |
[10] |
Sakorafas GH, Tsiotou AG. Etiology and pathogenesis of acute pancreatitis: current concepts[J]. J Clin Gastroenterol, 2000, 30(4):343-356.
pmid: 10875461 |
[11] |
Ballehaninna UK, Chamberlain RS. The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal[J]. J Gastrointest Oncol, 2012, 3(2):105-119.
doi: 10.3978/j.issn.2078-6891.2011.021 pmid: 22811878 |
[12] | 傅德良, 倪泉兴, 虞先濬, 等. 血清肿瘤标记物联合检测在胰腺癌诊治中的作用[J]. 外科理论与实践, 2001, 6(2):82-84. |
[13] |
Bracci PM, Wang F, Hassan MM, et al. Pancreatitis and pancreatic cancer in two large pooled case-control studies[J]. Cancer Causes Control, 2009, 20(9):1723-1731.
doi: 10.1007/s10552-009-9424-x URL |
[14] |
Carriere C, Young AL, Gunn JR, et al. Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras[J]. Biochem Biophys Res Commun, 2009, 382(3):561-565.
doi: 10.1016/j.bbrc.2009.03.068 URL |
[15] |
Conrad C, Fernandez-del Castillo C. Preoperative evaluation and management of the pancreatic head mass[J]. J Surg Oncol, 2013, 107(1):23-32.
doi: 10.1002/jso.23165 URL |
[16] | 李明欣, 尚东, 徐贺, 等. 首发症状为急慢性胰腺炎的胰腺癌诊断与治疗[J]. 中华消化外科杂志, 2014, 13(11):859-863. |
[17] |
Fan Z, Li Y, Yan K, et al. Application of contrast-enhanced ultrasound in the diagnosis of solid pancreatic lesions--a comparison of conventional ultrasound and contrast-enhanced CT[J]. Eur J Radiol, 2013, 82(9):1385-1390.
doi: 10.1016/j.ejrad.2013.04.016 URL |
[18] | 崔云涛. 胰腺癌的早期CT与MRI诊断[J]. 影像研究与医学应用, 2017, 1(17):117-118. |
[19] | 李亮, 程三房, 乔万海. 胰腺癌的多层螺旋CT及MRI影像学诊断分析[J]. 中国CT和MRI杂志, 2016, 14(8):4-6. |
[20] |
Wang Z, Chen JQ, Liu JL, et al. FDG-PET in diagnosis, staging and prognosis of pancreatic carcinoma: a meta-analysis[J]. World J Gastroenterol, 2013, 19(29):4808-4817.
doi: 10.3748/wjg.v19.i29.4808 URL |
[21] | Grino P, Martinez J, Grino E, et al. Acute pancreatitis secondary to pancreatic neuroendocrine tumours[J]. JOP, 2003, 4(2):104-110. |
[22] |
Kimura Y, Kikuyama M, Kodama Y. Acute pancreatitis as a possible indicator of pancreatic cancer: the importance of mass detection[J]. Intern Med, 2015, 54(17):2109-2114.
doi: 10.2169/internalmedicine.54.4068 URL |
[23] |
Pelletier AL, Hammel P, Rebours V, et al. Acute pancreatitis in patients operated on for intraductal papillary mucinous neoplasms of the pancreas: frequency, severity, and clinicopathologic correlations[J]. Pancreas, 2010, 39(5):658-661.
doi: 10.1097/MPA.0b013e3181c81b74 URL |
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