组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2014, Vol. 10 ›› Issue (4): 191-195.doi: 10.3969/j.issn.1673-0364.2014.04.004

• 论著 • 上一篇    下一篇

显微超声监测普萘洛尔治疗婴幼儿血管瘤的病情演变

常雷，仇雅璟，马刚，金云波，陈辉，于文心，杨希，胡晓洁，林晓曦   

  1. 上海交通大学医学院附属第九人民医院整复外科
  • 发布日期:2020-07-23

Microultrasound in Monitoring the Evolution of Infantile Hemangioma after Propranolol Treatment

CHANG Lei,QIU Yajing,MA Gang,JIN Yunbo,CHEN Hui,YU Wenxin,YANG Xi,HU Xiaojie,LIN Xiaoxi   

  1. Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine;
  • Published:2020-07-23
  • Contact: 国家自然科学基金面上项目（81272127）；上海市卫生系统重要疾病联合攻关重点项目（2013zyjb0014）

摘要： 目的应用显微超声监测腮腺区婴幼儿血管瘤患儿,在口服普萘洛尔前后病灶的变化情况。方法保存患儿普萘洛尔治疗前后的临床资料及超声图像并建立数据库,超声评价指标包括病灶深度、血管密度、血管阻力指数等,应用t检验分析治疗前后病灶变化情况。结果口服普萘洛尔后,血管瘤病灶深度、血管密度明显下降,血流阻力指数明显上升。结论普萘洛尔能够有效治疗婴幼儿血管瘤,显微超声能够有效监测服药后血管瘤病灶变化情况。

关键词: 显微超声, 普萘洛尔, 婴幼儿血管瘤, 血流动力学

Abstract: Objective To evaluate changes in parotid infantile hemangioma by using microultrasound before and after propranolol therapy. Methods Medical records and image studies of parotid hemangioma treated with propranolol were identified in a database. Evaluation criterion included the depth, vessel density and resisting index of focus. Student t test was used to evaluate changes before and after hemangioma treatment. Results The depth, vessel density were decreased and resisting index were increased after propranolol treatment. Conclusion Propranolol can treat infantile hemangioma effectively. Microultrasound can monitor the evolution of infantile hemangioma effectively.

Key words: Microultrasound, Propranolol, Infantile hemangioma, Hemodynamic

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