组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2017, Vol. 13 ›› Issue (5): 241-243.doi: 10.3969/j.issn.1673-0364.2017.05.001

• 小儿整形专题 •    下一篇

新生儿期脉冲染料激光治疗婴幼儿血管瘤的临床应用研究

张文显，高阳，杨伊帆，薛磊，李芳芳，曹敏娜   

  1. 河北省儿童医院整形外科
  • 收稿日期:2017-09-04 发布日期:2020-07-23

Clinical Application of the Pulsed Dye Laser for the Treatment of Infantile Hemangiomas in Neonates

ZHANG Wenxian,GAO Yang,YANG Yifan,XUE Lei,LI Fangfang,CAO Minna   

  • Received:2017-09-04 Published:2020-07-23
  • Contact: 河北省医学科学研究重点课题计划

摘要： 目的 探讨在新生儿期应用脉冲染料激光治疗婴幼儿血管瘤的可行性与安全性。方法 2015年1月至2017年3月,在新生儿期接受脉冲染料激光治疗的婴幼儿血管瘤患儿进行回顾性分析。所有患儿在治疗前均明确诊断为婴幼儿血管瘤,并且接受至少一次的脉冲染料激光治疗。治疗前后均进行拍照及超声检查。根据患儿血管瘤消退程度进行评分。结果 共112例患儿在新生儿时期进行了217次脉冲染料激光治疗,其中男性33例,女性79例。疗效评估认为,其中疗效不佳患儿5例,效果一般13例,效果良好27例,优秀67例。95.54%的患儿治疗有效,83.93%的患儿获得了良好及以上的治疗效果。6例患儿治疗后发生水泡,1例出现局部破溃。12例患儿在病灶完全消失后遗留局部色素沉着。结论 婴幼儿血管瘤患儿在新生儿期进行脉冲染料激光治疗是安全可行的。

关键词: 婴幼儿血管瘤, 新生儿, 脉冲染料激光

Abstract: Objective To explore the feasibility and safety of the pulsed dye laser (PDL) for the treatment of infantile hemangiomas in neonates. Methods From January 2015 to November 2016, neonates with infantile hemangiomas treated by PDL were retrospectively analyzed. All patients were diagnosed as infantile hemangiomas and accepted at least one time of therapy. Photo and ultrasound were taken before and after treatment. The neonates were graded according to the degree of regression of hemangioma. Results A total of 112 neonates (33 males, 79 females) with infantile hemangiomas accepted 217 times of PDL therapy. The therapeutic effects of these neonates were evaluated, including 5 cases with poor effects, 13 cases in general, 27 cases with good results and 67 excellent cases. 95.54% patients got acceptable results, 83.93% patients achieved good or better results. After treatment, blisters were observed in 6 patients and partial rupture was observed in one patient. Twelve patients left hyperpigmentation after the hemangiomas were cured. Conclusion PDL is a safe and effective method for the treatment of infantile hemangiomas in neonates.

Key words: Infantile hemangioma, Neonate, Pulsed dye laser

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