组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2017, Vol. 13 ›› Issue (3): 149-152.doi: 10.3969/j.issn.1673-0364.2017.03.009

• 论著 • 上一篇    下一篇

1540nm铒玻璃非剥脱点阵激光改善痤疮后遗皮损的疗效观察

石钰，章伟   

  1. 上海市皮肤病医院医学美容科
  • 发布日期:2020-07-23

Efficacy of Non-Ablative 1540 nm Erbium-Glass Fractional Laser on Facial Post-Acne Lesions

SHI Yu,ZHANG Wei   

  • Published:2020-07-23

摘要： 目的 观察1540 nm铒玻璃非剥脱点阵激光,用于治疗痤疮后遗皮损(凹陷性瘢痕、毛孔粗大、痤疮红斑、色素沉着等)的临床疗效和安全性.方法 随机选取面部痤疮后遗皮损患者28名,采用1540 nm铒玻璃非剥脱点阵激光,治疗3~9次,每次间隔4周,于末次治疗1个月后观察疗效.使用四级法、VISIA皮肤图像分析仪评估疗效,用CK皮肤检测仪评估皮肤屏障功能.结果 1540 nm铒玻璃非剥脱点阵激光对痤疮后凹陷性瘢痕、毛孔粗大、痤疮红斑和色素沉着的有效率分别为14.29%、25%、34.76%和18.18%.VISIA显示,治疗前后毛孔、红区、紫质的绝对分值的差异有统计学意义(P<0.05),疗效与治疗次数成正相关.治疗前后经表皮失水率(Trans-epidermis water loss,TEWL)和皮肤油脂含量无明显差异(P>0.05).本组患者治疗过程中未发现严重不良反应.结论 1540 nm铒玻璃非剥脱点阵激光可以安全有效、较全面地治疗痤疮后遗皮损,尤其推荐用于毛孔粗大和痤疮红斑的改善.

关键词: 铒玻璃, 点阵激光, 痤疮瘢痕

Abstract: Objective To evaluate the clinical efficacy and safety of non-ablative 1540 nm erbium-glass fractional laser on treating facial post-acne lesions, including atrophic scars, enlarged pores, post-acne erythema and post-inflammatory hyperpigmentation (PIH). Methods A non-ablative 1540 nm erbium-glass fractional laser was used to treat 28 patients. All patients were treated for 3-9 times with an interval of 4-week. The efficacy was assessed by A quartile grading scale, VISIA complexion analysis system and CK skin property 1 month after treatment. Results The efficacy rate of non-ablative 1540 nm erbium-glass fractional laser was 14.29% for post-acne scars, 25% for enlarged pores, 34.76% for post-acne erythema and 18.18% for PIH. Compared to pre-therapy, there was significant difference in pores, erythema and purple mass, and there was positive correlation between efficacy and treatment frequencies (P0.05). No severe adverse effect was observed. Conclusion Non-ablative 1540 nm erbium-glass fractional laser was safe and effective in treating post-acne skin lesions, especially for post-acne erythema and enlarged pores.

Key words: Erbium glass, Fractional laser, Post-acne lesions

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