组织工程与重建外科杂志 ›› 2025, Vol. 21 ›› Issue (1): 36-.

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曲安奈德联合平阳霉素治疗微囊型淋巴管畸形的疗效分析

  

  • 出版日期:2025-02-25 发布日期:2025-03-06

Analysis of the therapeutic effect of combination therapy with triamcinoloneacetonide and pingyangmycin on microcystic lymphatic malformations

  • Online:2025-02-25 Published:2025-03-06

摘要:

目的 探讨曲安奈德联合平阳霉素治疗微囊型淋巴管畸形的疗效。方法 2022年3月至2024年3月,48例微囊型淋巴管畸形患儿分为两组:曲安奈德联合平阳霉素治疗组(实验组)和单纯平阳霉素治疗组(对照组),比较两组患儿分别治疗 1次、2次、3次后的治愈率及并发症发生率。结果 实验组治疗 1次、2次、3次后的治愈率分别为 32.00%、60.00%、92.00%,对照组分别为 4.35%、30.43%、60.87%。两组 3次治疗后的治愈率均明显高于 1次治疗后(P<0.001),每次治疗后实验组治愈率均高于对照组(P<0.05)。实验组并发症发生率(12.00%)低于对照组(39.13%),差异具有统计学意义(P<0.05)。结论 曲安奈德联合平阳霉素治疗微囊型淋巴管畸形能提高治愈率并减少并发症发生率,可作为一种更优的临床治疗选择。

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Abstract:

Objective To explore the therapeutic effect of triamcinolone acetonide combined with pingyangmycin in the treatment of microcystic lymphatic malformations. Methods From March 2022 to March 2024,48 children with microcystic lymphangioma were divided into two groups, namely the experimental group treated with combination of triamcinolone acetonide and pingyangmycin and the control group treated with pingyangmycin alone. The cure rate after 1,2 and 3 treatments and complication rate of the two groups were compared. Results The cure rate of the experimental group after 1, 2, and 3 treatments were 32.00% 60.00%, and 92.00%, respectively, while those of the control group were 4.35%, 30.43%, and 60.87%, respectively. The cure rate of the two groups after 3 treatments was significantly higher than that after 1 treatment (P<0.001); After each treatment, the cure rate of the experimental group was higher than that of the control group (P<0.05). The complication rate of the experimental group (12.00%) was lower than that of the control group (39.13%), and the difference was statistically significant (P<0.05). Conclusion The combination of triamcinolone acetonide and pingyangmycin in the treatment of microcystic lymphatic malformations can improve the cure rate and reduce the incidence of complications, and can be a better clinical treatment option.

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