Journal of Tissue Engineering and Reconstructive Surgery ›› 2009, Vol. 5 ›› Issue (3): 128-130.doi: 10.3969/j.issn.1673-0364.2009.06.003

• Original article • Previous Articles     Next Articles

An Experimental Study on Reconstruction of Acellular Dermal Matrix Carried PDGF-BB and IGF-1

LIU Cheng,FU Jinsong,LIU Shan,ZHOU Zengding,SONG Zhiyong   

  1. Jiangxi Provincial People s Hospital;Nanchang 330006;China.;
  • Published:2020-07-23
  • Contact: 江西省卫生局课题(20083011)

Abstract: Objective To explore the reconstruction of acellular dermal matrix carried PDGF-BB and IGF-1 in vitro.Also investigate cultured human fibroblast proliferation and collagen production affected by constructed acelluar dermal matrix.Methods The degraded micro beads with PDGF-BB and IGF-1 were synthe-sized and connected to acellular dermal matrix.Acelluar dermal matrix was cultured with fibroblast.Fibroblast proliferation rate and cell variability were observed by cell count and WST-8 colorimeter;The release of...

Key words: Acellular artificial dermal matrix, PDGF-BB, IGF-1, Micro bead

CLC Number: