Journal of Tissue Engineering and Reconstructive Surgery ›› 2009, Vol. 5 ›› Issue (4): 186-189.doi: 10.3969/j.issn.1673-0364.2009.08.002

• Original article • Previous Articles     Next Articles

Preliminary Study on influence of Chitosan-Collagen Compound with Different ratio for Cell Affinity

YANG Yang,DENG Dan,LIU Wei,YANG Yaofei   

  1. Shanghai Tissue Engineering Research and Development Center;Shanghai 200235;China
  • Published:2020-07-23
  • Contact: 上海交通大学医工(理)交叉研究基金项目(YG2009MS34)

Abstract: Objective To investigate the influence of chitosan-collagen compound with different ratio for cell affinity and physical variation of the scaffold. Methods Human dermal fibroblasts of passage 3 were cultured and amplified in vitro, then seeded on the those scaffolds in different mixed ratio groups as follows: 100% collagen as group 1, 70% collagen (chitosan-collagen mixed with 3∶7) as group 2, 50% collagen (chitosan-collagen mixed with 5∶5) as group 3, 30% collagen (chitosan-collagen mixed with 7∶3) as grou...

Key words: Chitosan, Collagen, Human dermal fibroblast, Cell affinity

CLC Number: