Abstract: Objective To explore the effect of high dose, decentralized, multi-level autologous fat grafting in modified breast augmentation with areola incision. Methods From January 2013 to December 2014, 35 women (67 breasts) were received autologous fat injection. Autologous fat was obtained from patient ’s thighs by tumescent liposuction technique. After gotten rid of fibrous insulation, blood and water, autologous fat was injected by means of a blunt needle with the diameter of 2 mm in multiple layers (subcutaneous space, retro-mammary space, pectoralis major muscle and post-pectoralis major muscle space) and multiple tubes through the areola incision at 3 or 9 o'clock direction. The breast shape, volume and chest circumference were assessed within 24 months. The data were analyzed and compared. Results All the patients were followed up for 6 to 24 months. The breast shape, volume, and chest circumference were basically achieved a stable status in all the 35 cases six months after operation, and satisfactory cosmetic results were achieved. No complications such as breast masses or nodules were observed. According to the close follow-up of typical cases, 6 months after injection, the survival rate of grafted fat was over 75%, chest circumference increased by an average of 5.4 cm. Conclusion Large-volume autologous fat grafting through areola incision is a valuable method for breast augmentation with high survival rates, high safety and satisfactory efficacy.

Key words: Areola incision, Augmentation mammoplasty, Autologous fat, Transplantation