Abstract: Objective To investigate the effectiveness of dexmedetomidine combined with dizosin in anesthesia for liposuction.Methods Sixty patients undergoing liposuction were reviewed and randomly divided into 2 groups:observation group(n=30)and control group(n=30).In observation group,dexmedetomidine combined with dizosin were taken for intravenous anesthesia,while midazolam combined with remifentanil were taken for intravenous anesthesia in control group.Scoring criteria included Ramsay sedation score,VAS pain score and HR,MAP,SpO2 at different time points were all observed.Recovery time and awake time of the two groups were recorded.The adverse reactions were observed.Results The respiratory rate and oxygen saturation at T1,T2,T3 and T4 in the observation group were higher than those in the control group and the heart rate and mean arterial pressure at T3,T4 were lower than those in the control group(P<0.05).The recovery time and awake time in observation group were shorter than those in control group(P<0.05).The incidence rate of postoperative restlessness and oxygen saturation<92%were both lower in the observation group than in the control group(P<0.05).Conclusion For the patients undergoing liposuction,dexmedetomidine combined with dizosin as intravenous anesthesia has good effect,it has advantages of shorter recovery and awake time,lower incidence of adverse reactions,and higher safety.

Key words: Dexmedetomidine, Dizosin, Liposuction