Journal of Tissue Engineering and Reconstructive Surgery ›› 2022, Vol. 18 ›› Issue (4): 345-.

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Application of bioactive glasses on soft tissue repair 

  

  • Online:2022-08-01 Published:2022-09-07

Abstract: Bioactive glasses (BGs) have been widely used in regenerative medicine and tissue engineering. It can produce hydroxy carbonate apatite (HCA) when contact with body fluids, and thus closely bind with bone tissue, so it is often used in the replacement, regeneration and repair of bone defects or teeth. With the development of technology and bioactive materials, more and more evidence has proved the potential of BGs in soft tissue repair. BGs itself has antibacterial effect, which has obvious advantages in soft tissue repair. By changing its composition or combining with different materials such as functional ions, polymers and biological factors, BGs can promote wound healing more quickly and effectively. In this paper, the development of BGs was reviewed, and the possible mechanism of BGs accelerating wound repair was discussed by comparing with the mechanism of wound repair. Finally, the research trend of BGs in wound repair was interpreted.

Key words: Bioactive glasses,  Wound healing,  Tissue engineeringt