Abstract: Wound healing involves complicate pathophysiological process. With the mechanism of wound healing elucidated, wound healing has improved in a large extent as the result of new techniques and materials application. This paper focused on concluding the feature, principle, influence factors of supercritical fluid extraction (SFE) technique of CO2 and the research progress of this technique in wound healing, and provided the information of SFE in wound healing for further research of SFE in this field. 

Key words: Supercritical fluid extraction, 　Carbon dioxide, 　Wound healing