Journal of Tissue Engineering and Reconstructive Surgery ›› 2022, Vol. 18 ›› Issue (5): 450-.

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Research progress of extracellular vesicles secreted by adipose-derived stem cells in improving the survival rate of fat grafting

  

  • Online:2022-10-01 Published:2022-11-07

Abstract: Fat grafting has been widely used in the reconstruction of tissue defects, cosmetic filling, or other fields. The improvement of survival rate is of great importance in fat grafting. Extracellular vesicles (EVs) secreted by adipose-derived stem cells improved the survival rate of fat grafting when co-transplanted with granular fat. The definition, extraction, transplantation methods of EVs, and the mechanism of EVs in improving the survival rate of fat grafting were reviewed. The shortcomings of existing studies on EVs were summarized, and the direction for future studies were also provided in this review.

Key words: Adipose-derived stem cells,  , Extracellular vesicles,  , Fat grafting,  , Survival rate