Application of Exosome Derived from Adipose Derived Stem Cells in Promoting Tissue Repair

doi:10.3969/j.issn.1673-0364.2018.04.011

Journal of Tissue Engineering and Reconstructive Surgery ›› 2018, Vol. 14 ›› Issue (4): 219-222.doi: 10.3969/j.issn.1673-0364.2018.04.011

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Application of Exosome Derived from Adipose Derived Stem Cells in Promoting Tissue Repair

CHEN Chuhsin,ZHOU Shuangbai,LI Qingfeng

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine

Received:2018-03-28 Revised:2018-05-23 Published:2020-07-23
Contact: 国家自然科学基金青年项目(81501678)；国家自然科学基金重点国际合作项目(81620108019)

Abstract

Abstract: Adipose-derived stem cells have the effect of promoting tissue repair and regeneration, and its mechanism of action is inseparable from its paracrine role. Exosomes are extracellular vesicle secreted by cells and are a new mechanism for communication between cells. In recent studies, it has been found that stem cell-derived exosomes are a major means of paracrine activity of stem cells and mediate their role in promoting tissue regeneration. The application of exosomes provides a new strategy for tissue repair. In this paper, the application of exosomes derived from adipose-derived stem cells in tissue regeneration was reviewed.

Key words: Adipose-derived stem cells, Exosome, Extracellular vesicle, Tissue repair

CLC Number:

R329.2

CHEN Chuhsin,ZHOU Shuangbai,LI Qingfeng. Application of Exosome Derived from Adipose Derived Stem Cells in Promoting Tissue Repair[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2018, 14(4): 219-222.

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Application of Exosome Derived from Adipose Derived Stem Cells in Promoting Tissue Repair

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