Journal of Tissue Engineering and Reconstructive Surgery ›› 2023, Vol. 19 ›› Issue (1): 22-.

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 Efficacy analysis of‘core stripping’keloid thinning surgery combined with radiotherapy

  

  • Online:2023-02-01 Published:2023-03-08

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Abstract:

Objective　To explore the effect of "core stripping" keloid thinning surgery combined with radiotherapy in the
treatment of keloid. Methods　From January 2020 to December 2020, 43 patients with slope keloid and 326 keloid lesions
were selected by retrospective study and self-control. The "core stripping" keloid thinning surgery was used to separate and
remove the core tissue of keloid while retaining the scar skin with a thickness of about 1 mm. The reticular dermis was retained,
and the scar skin was sutured and fixed by the "modified mattress suture method". After surgery, 6 Mev electron radiotherapy
was performed twice. The first radiotherapy was completed within 24 hours after operation, and the second radiotherapy was
performed 7 days later. The single dose of radiotherapy was 9 Gy. Follow-up was performed at 6 months, 12 months and 18
months after the end of treatment. The patient and observer scar scale (POSAS) was used to analyze the treatment outcomes, and 
the treatment response rate and patients' satisfaction at 18 months after treatment were statistically analyzed. Results　The total
score of POSAS, total score of patients, and total score of observers were significantly lower after treatment than before treatment.
Some patients had different degrees of hyperpigmentation, hypopigmentation, local hair loss, transient dermatitis and neuritis,
which improved spontaneously. The total recurrence rate at 18 months after treatment was 30.23%. Among 43 keloid patients, 17
patients (39.53%) were very satisfied with the treatment outcome, 22 patients (51.62%) were satisfied, and 4 patients (9.3%) were
not satisfied. The overall satisfaction rate was 90.7%. Conclusion　The "core stripping" keloid thinning surgery is a rapid and
effective keloid volume reduction surgery, which has a good therapeutic effect when combined with postoperative radiotherapy.

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