Journal of Tissue Engineering and Reconstructive Surgery ›› 2023, Vol. 19 ›› Issue (3): 298-.

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Research progress of three dimensional bio-printing technology for formation of vascular network in bone tissue

  

  • Online:2023-06-01 Published:2023-07-05

Abstract:

Vascularization of bone grafts is one of the major challenges facing bone tissue engineering (BTE). The ultimate
goal of the construction of vascularized BTE is to provide a bone environment rich in functional vascular networks to achieve
efficient bone integration and accelerate the functional recovery after implantation. In this paper, the research progress of 3D
bio-printing in the formation of vascular network in bone tissue was reviewed, the formation mechanism of vascular network and
the characteristics of 3D bio-printing technology were elaborated, the current vascularization strategies in BTE were summarized,
and its development prospects were prospected.

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