Abstract:

　Soft tissue defects of skin are common in clinical practice. The restoration of dermal damage, to a large ex

tent, contributes to the repairing effects and scar formation of skin soft tissue defects. Three-dimensional (3D) bioprinting is an

emerging technology that can accurately distribute biomaterials and living cells. It creates intricate stereoscopic structures which

facilitates regenerative repair of dermal defects. Due to limitations of printing method, bio-ink, and seed cells, 3D bioprinting

technology for skin is still in the lab stage. With the development of 3D bioprinting, especially in novel bio-ink exploitation and

technical optimization, high resolution 3D bioprinting will enable us to customize elaborate functionalized skin models and even

cutaneous appendages, providing new strategies in dermal regenerative repairment.

Key words:

3D bioprinting, 　Dermis, 　Wound healing, 　Skin tissue engineering