Journal of Tissue Engineering and Reconstructive Surgery ›› 2020, Vol. 16 ›› Issue (3): 198-200.doi: 10.3969/j.issn.1673-0364.2020.03.006

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Case Report: Clinical Attempt of Targeted Therapy for Complex Venous Malformations

Hongyuan LIU, Xi YANG, Hao GU, Li HU, Yi SUN, hui CHEN(), Xiaoxi LIN()   

  1. Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
  • Received:2020-04-16 Revised:2020-04-29 Online:2020-07-27 Published:2020-06-26

Abstract: The management of severe and complicated venous malformation is still not standardized currently. Sirolimus has been reported to successfully treat complicated vascular anomalies in many case reports and clinical trials recently. One case of extremely severe and complicated venous malformation of right upper limb and trunk was described. After 2 years of oral treatment with sirolimus, the lesion was significantly resolved, and no obvious recurrence was found after 1 year of follow-up.

Key words: Venous malformation, Sirolimus, Vascular malformation, Target therapy

CLC Number: