Journal of Tissue Engineering and Reconstructive Surgery ›› 2020, Vol. 16 ›› Issue (3): 198-200.doi: 10.3969/j.issn.1673-0364.2020.03.006
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Hongyuan LIU, Xi YANG, Hao GU, Li HU, Yi SUN, hui CHEN(), Xiaoxi LIN(
)
Received:
2020-04-16
Revised:
2020-04-29
Online:
2020-07-27
Published:
2020-06-26
CLC Number:
Hongyuan LIU, Xi YANG, Hao GU, Li HU, Yi SUN, hui CHEN, Xiaoxi LIN. Case Report: Clinical Attempt of Targeted Therapy for Complex Venous Malformations[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2020, 16(3): 198-200.
Fig. 2
Patient's photographs before and after treatment A: Before sirolimus therapy; B: After sirolimus therapy for 1 year; C: After sirolimus therapy for 2 years; D: After withdrawal for 1 year (Red arrows: After sirolimus therapy, localized microwave treatment of upper limb and chest was attempted, remaining scar contractions)
[1] | 中华医学会整形外科分会血管瘤和脉管畸形学组. 血管瘤和脉管畸形的诊断及治疗指南(2019版)[J]. 组织工程与重建外科杂志, 2019,15(5):277-317. |
[2] | Freixo C, Ferreira V, Martins J , et al. Efficacy and safety of sirolimus in the treatment of vascular anomalies: A systematic review[J]. J Vasc Surg, 2020,71(1):318-327. |
[3] | Soblet J, Kangas J, Natynki M , et al. Blue rubber bleb nevus (BRBN) syndrome is caused by somatic TEK (TIE2) mutations[J]. J Invest Dermatol, 2017,137(1):207-216. |
[4] | Castel P, Carmona FJ, Grego-Bessa J , et al. Somatic PIK3CA mutations as a driver of sporadic venous malformations[J]. Sci Transl Med, 2016, 8(332):332ra42. |
[5] | Adams DM, Trenor CC 3rd, Hammill AM, et al. Efficacy and safety of sirolimus in the treatment of complicated vascular anomalies[J]. Pediatrics, 2016,137(2):e20153257. |
[6] | Hammer J, Seront E, Duez S , et al. Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study[J]. Orphanet J Rare Dis, 2018,13(1):191. |
[7] | Hammill AM, Wentzel M, Gupta A , et al. Sirolimus for the treatment of complicated vascular anomalies in children[J]. Pediatr Blood Cancer, 2011,57(6):1018-1024. |
[8] | Lackner H, Karastaneva A, Schwinger W , et al. Sirolimus for the treatment of children with various complicated vascular anomalies[J]. Eur J Pediatr, 2015,174(12):1579-1584. |
[9] | Morelon E, Stern M, Israel-Biet D , et al. Characteristics of sirolimus-associated interstitial pneumonitis in renal transplant patients[J]. Transplantation, 2001,72(5):787-790. |
[10] | Russell TB, Rinker EK, Dillingham CS , et al. Pneumocystis jirovecii pneumonia during sirolimus therapy for kaposiform hemangioendo the lioma[J]. Pediatrics, 2018,141(Suppl 5):S421-S424. |
[11] | Fujii T, Shimono R, Tanaka A , et al. A case of suspected adverse reactions to sirolimus in the treatment of generalized lymphatic anomaly[J]. Case Rep Pediatr, 2019,2019:3101357. |
[12] | Ying H, Qiao C, Yang X , et al. A case report of 2 sirolimus-related deaths among infants with kaposiform hemangioendotheliomas[J]. Pediatrics, 2018,141(Suppl 5):S425-S429. |
[13] | Goldenberg DC, Carvas M, Adams D , et al. Successful treatment of a complex vascular malformation with sirolimus and surgical resection[J]. J Pediatr Hematol Oncol, 2017,39(4):e191-e195. |
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