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26 June 2020, Volume 16 Issue 3 Previous Issue    Next Issue

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A Clinical Study of Different Concentrations of Timoiol Maleate Eye Drops for the Treatment of Superficial Infantile Hemangiomas Shengmiao LI, Chunfen LUO, Jiachuan XU, Linjun YU 2020, 16 (3):  179-181.  DOI: 10.3969/j.issn.1673-0364.2020.03.001 Abstract ( 805 )   HTML ( 563 )   PDF (1010KB) ( 351 )   Objective To explore the efficacy and safety of timolol maleate eye drops with different concentrations for the treatment of superficial infantile hemangiomas. Methods From January 2018 to January 2019, patients aged within 6 months with superficial infantile hemangiomas were enrolled, and were randomly divided into 2 groups according to different concentration of timolol maleate eye drops: 0.25% timolol group and 0.5% timolol group. Tiamolol maleate eye drops were applied externally by wet compressing for 20 minutes, three times a day for 6 months. The therapeutic effect was categorized into four grades, the therapeutic effect and safety of the two groups were compared. Results A total of 87 patients with superficial infantile hemangiomas were included in the study and were divided into 0.25% timolol group (n=41) and 0.5% timolol group (n=46). Six months after treatment, the effective rate and cure rate of 0.25% timolol group were 63.4% and 14.6%, the effective rate and cure rate of 0.5% timolol group were 82.6% and 19.6%. The effective rate of 0.5% timolol group was significantly higher than that of 0.25% timolol group (P<0.05). There was no significant difference of cure rate between the two groups (P>0.05). No severe systemic or local adverse reactions were observed during treatment. Conclusion Topical application of timolol maleate eye drops in the treatment of superficial infantile hemangiomas during proliferative phase is simple, effective and safe. Drug concentration may be one of the factors influencing clinical efficacy. Figures and Tables | References | Related Articles | Metrics

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Sclerotherapy Using Polidocanol Injectable Foam Combined with Pinyangmycin in the Treatment of Venous Malformation in Tongue of Preschoolers Liang WANG, Changhua WU, Dan SONG, Jing LI, Jie ZHOU, Xin ZHANG, Lei GUO 2020, 16 (3):  182-185.  DOI: 10.3969/j.issn.1673-0364.2020.03.002 Abstract ( 623 )   HTML ( 532 )   PDF (816KB) ( 446 )   Objective To evaluate the clinical efficacy and safety of sclerotherapy using polidocanol injectable foam combined with pinyangmycin in the treatment of venous malformation in tongue of preschoolers. Methods From January 2017 to December 2018, 26 preschoolers with venous malformation in tongue treated with sclerotherapy were retrospectively analyzed. Intraoperatively, the tongue lesions were punctured from multiple angles, and after the blood was recovered, contrast agent was injected for DSA angiography, and polidocanol injectable foam or pingyangmycin was injected under DSA fluoroscopy. The general information, clinical manifestations, imaging data, therapeutic effect and complications were all recorded. Results A total of 72 sclerosing treatments were performed in 26 patients, with an average of 2.77 sclerosing treatments per patient (1-4 sclerosing treatments per patient). The clinical symptoms of all the children were relieved to different degrees, among which 4 cases were cured, 20 cases were basically relieved, and 2 cases were effective, with an overall effective rate of 100%. Short-term complications included mild swelling (23 cases) and fever (4 cases). No serious complications was observed in the 26 cases. Conclusion Sclerotherapy using polidocanol injectable foam combined with pinyangmycin is an effective and safe method with few side effect for the treatment of venous malformations in tongue of preschoolers, and is worthy of clinical promotion. Figures and Tables | References | Related Articles | Metrics

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Rebound Growth of Propranolol Therapy for the Treatment of Medium and High Risk Infantile Hemangiomas Xilan CHEN, Xiao LIN, Yun YANG, Ying HUANG, Jing ZHOU, Qiufang QIAN 2020, 16 (3):  186-189.  DOI: 10.3969/j.issn.1673-0364.2020.03.003 Abstract ( 490 )   HTML ( 321 )   PDF (1046KB) ( 282 )   Objective To study the efficacy and rebound growth of propranolol for the treatment of medium and high risk infantile hemangiomas. Methods From March 2013 to March 2015, 151 cases with medium and high risk infantile hemangiomas were treated with oral propranolol. The dose of oral propranolol started at 0.5 mg/Kg·d with an increase by 0.25 mg/Kg·d everyday at the first 3 days, up to 1.0 mg/Kg·d, and the maximum dose was 2 mg/Kg·d. Complete blood tests and doppler ultrasound were obtained before, during and after treatment. The total treatment cycle last 6-12 months, with a 3-year period of follow-up study for clinical observation. Results A total of 151 patients were enrolled, and 141 patients completed the therapy and follow-up, the completion rate was 93.38%. The average age of first therapy was 2.32±0.85 months, the average duration of oral propranolol was 9.61±4.06 months. There were 55 (39.01%) patients had rebound growth during propranolol therapy. The patients whose first therapy age under 6-month had the higher risk of rebound growth, but there was no statistically significant difference (P>0.05). The pathogenic site of head and face region hemangiomas had the higher risk of rebound growth than other regions (P<0.05). Conclusion Oral propranolol in the treatment of hemangioma can appear rebound growth, so it is recommended to gradually reduce the dosage and lengthen the medication period to reduce rebound and recurrence. Figures and Tables | References | Related Articles | Metrics

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Clinical Analysis for Post-Treatment Tissue Atrophy of Hemangiomas and Vascular Malformations: 353 cases Zhen MENG, Renrong LV, Li LIN, Ran HUO 2020, 16 (3):  189-192.  DOI: 10.3969/j.issn.1673-0364.2020.03.004 Abstract ( 479 )   HTML ( 38 )   PDF (1105KB) ( 258 )   Objective To investigate the relative factors of local tissue atrophy after treatment of hemangioma (HA) and vascular malformation (VM). A retrospective analysis was performed on 353 HA or VM patients from January 2010 to December 2012, and statistical analysis was performed on the factors that may be related to the occurrence of local tissue atrophy. Results Among the 353 cases, 17 cases suffered tissue atrophy. The overall incidence of tissue atrophy was 4.82%. Single factor analysis of variance showed that isotope therapy, ulceration and sclerotherapy only were the factors affecting local tissue atrophy (P<0.05). Gender, age, type, cryotherapy had no obvious relation with the occurrence of tissue atrophy (P>0.05). Followed multivariate logistic regression analysis showed that isotope therapy and ulceration were independent risk factors for tissue atrophy, and sclerotherapy only was a protected factor. Conclusion Sclerotherapy is recommended as the main treatment mean of HA and VM, because of its satisfactory effects on the treatment and low incidence of tissue depression. Nonetheless, the principle of injection should be strictly observed. Isotopic therapy and ulceration are two independent risk factors for tissue atrophy. Figures and Tables | References | Related Articles | Metrics

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The Effect of Optical Clearing Agent on the Treatment of Port-Wine Stains by Pulsed Dye Laser Yanyu CHEN, Wenxin YU, Gang MA, Xiaoxi LIN 2020, 16 (3):  193-197.  DOI: 10.3969/j.issn.1673-0364.2020.03.005 Abstract ( 493 )   HTML ( 20 )   PDF (1207KB) ( 217 )   Objective To explore the ef?cacy of optical clearing agent (OCA) on the treatment of port wine stain (PWS) using pulsed dye laser (PDL). Methods The lesions of 13 patients with PWS were divided into two treatment areas. One of the areas was treated by PDL after applying OCA (OCA+PDL area), the other one was treated by PDL only (PDL area). Each patient underwent three sessions with interval of 2 months. Chromameter and visual evaluation (VAS) were used to evaluate the ef?cacy and side effects of each area three months after the final sessions. Results After three sessions of treatment, the chromameter and visual evaluation suggested no significant difference between each area. However, after the first session, the VAS of OCA+PDL area and PDL area were 2.69 and 2.07, respectively, showing a significant difference (P=0.025), suggesting that the former had a significant improvement in color spots after one single session. Permanent side effects were not observed in any patient. Conclusion Compared with single use of PDL, the combined use of OCA does not improve the efficacy of PDL in treating PWS. Figures and Tables | References | Related Articles | Metrics

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Case Report: Clinical Attempt of Targeted Therapy for Complex Venous Malformations Hongyuan LIU, Xi YANG, Hao GU, Li HU, Yi SUN, hui CHEN, Xiaoxi LIN 2020, 16 (3):  198-200.  DOI: 10.3969/j.issn.1673-0364.2020.03.006 Abstract ( 731 )   HTML ( 75 )   PDF (1535KB) ( 378 )   The management of severe and complicated venous malformation is still not standardized currently. Sirolimus has been reported to successfully treat complicated vascular anomalies in many case reports and clinical trials recently. One case of extremely severe and complicated venous malformation of right upper limb and trunk was described. After 2 years of oral treatment with sirolimus, the lesion was significantly resolved, and no obvious recurrence was found after 1 year of follow-up. Figures and Tables | References | Related Articles | Metrics

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Case Report: Traumatic Pseudoaneurysm of the Superficial Temporal Artery Tianye YANG, Haodong WANG, Jingyue Zhang, Meng LIU, Li RONG 2020, 16 (3):  201-203.  DOI: 10.3969/j.issn.1673-0364.2020.03.007 Abstract ( 725 )   HTML ( 34 )   PDF (1701KB) ( 256 )   Two cases of spontaneous resolution of traumatic pseudoaneurysm of the superficial temporal artery were reported. All the 2 patients had a history of head trauma, and there was a mass in the temporal region after the injury, which was indicated by ultrasound as pseudosuperficial temporal aneurysm. The tumor disappeared after conservative treatment. Follow-up was conducted for 6-8 months, and no recurrence was found. Some traumatic pseudosuperficial temporal aneurysms can heal spontaneously after the acute stage without surgery intervention, and the tumor disappears. Figures and Tables | References | Related Articles | Metrics

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Progress in Targeted Therapy of Low-Flow Vascular Malformation Hongyuan LIU, Tongxin GE, Xiaoxi LIN 2020, 16 (3):  204-209.  DOI: 10.3969/j.issn.1673-0364.2020.03.008 Abstract ( 646 )   HTML ( 70 )   PDF (754KB) ( 306 )   With the introduction of the concept of precision medicine and the breakthrough in the genetics of vascular malformation, developing targeted therapies for low-flow vascular malformation has become a hot spot and urgent task of current research. Low-flow vascular malformation has been confirmed by the presence of somatic activation mutations leading to the continuous activation of the PI3K/AKT/ mTOR pathway, which indicates the possibility of targeted therapies. In this paper, the current researches and applications of targeted drugs in the treatment of low-flow vascular malformation were reviewed. References | Related Articles | Metrics

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Progress of Diagnosis and Treatment of Verrucous Venous Malformation Lili QIAN, Yajing QIU, 2020, 16 (3):  210-213.  DOI: 10.3969/j.issn.1673-0364.2020.03.009 Abstract ( 954 )   HTML ( 251 )   PDF (766KB) ( 457 )   Verrucous venous malformation, formerly known as verrucous hemangioma, is a rare congenital vascular abnormality. It usually appears at birth or in early childhood. It enlarges with body growth and does not regress spontaneously. The early lesions are red in color, with clear boundaries. But in time they become increasingly hyperkeratotic and verrucous. It is generally accepted that surgical excision is the first choice of treatment. The incomplete excision would lead to recurrence of the lesion from the deeper components. Cryosurgery, electrocautery, laser therapy or sclerotherapy can be used to combine with surgical resection, to prevent recurrence or delay the development of lesions. In this paper, the diagnosis and treatment of verrucous venous malformation were reviewed, in order to guide the clinical diagnosis and treatment of verrucous venous malformation. References | Related Articles | Metrics

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Pedicled Expanded Trunk Flap in the Treatment of Congenital Giant Nevus of Upper Extremity Xiaoning YANG, Jie LI, Xin LI, Lu YU, Keming WANG, Chunhu WANG, Meng WANG, Xuebing LIANG, Jiguang MA 2020, 16 (3):  216-219.  DOI: 10.3969/j.issn.1673-0364.2020.03.011 Abstract ( 426 )   HTML ( 34 )   PDF (1484KB) ( 225 )   Objective To explore the effect of pedicled expanded trunk flap in the treatment of congenital giant nevus of upper extremity in children. Methods From January 2015 to December 2016, 7 cases of congenital giant nevus of upper extremity were treated with pedicled expanded trunk flap. The operation can be divided into 3 stages: Tissue expanders were implanted into the trunk in Stage Ⅰ; After proper expansion, the giant nevus was resected and the expanded flap was transferred to the upper extremity to establish blood circulation in Stage Ⅱ; Pedicle transection was performed in Stage Ⅲ. Results The size of the nevus was 16 cm×10 cm to 30 cm×14.5 cm, all giant nevi were completely removed. All patients were followed up for 6 to 39 months (mean 25.5 months). All the flaps survived with good blood supply, the color and texture were similar to the surrounding normal skin, and there were no complications such as infection, hematoma, necrosis and contracture. For cases involving periarticular skin, postoperative joint movements were normal. Expander exposure was noted in 1 case, but had no negative effect on the result. Conclusion Pedicled expanded trunk flap can provide large areas of normal skin and avoid multiple expansions. It is practical and effective. It is a reliable method to repair the defect of upper extremity. Figures and Tables | References | Related Articles | Metrics

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The Postoperative Comparison of the Auricular Reconstruction Between the Dilator Method Retaining the Superficial Temporal Fascia and the Posterior Ear Fascial Flap Method Jingjing WANG, Jia ZOU, Hui SONG, Xiaowei TANG, Chengwang GE, Wei CAI, Lei LI, Gan SHEN 2020, 16 (3):  220-222.  DOI: 10.3969/j.issn.1673-0364.2020.03.012 Abstract ( 433 )   HTML ( 23 )   PDF (2391KB) ( 193 )   Objective To compare the clinical effects of the auricular reconstruction between the dilator method retaining the superficial temporal fascia and the posterior ear fascial flap method . Methods From January 2010 to January 2019, the clinical data of 118 patients with microtia was retrospectively analyzed and the patients were divided into experimental group (n=105) and control group (n=13) according to the different operation method. In the experimental group, three-stage auricular reconstruction technique retaining the superficial temporal fascia was performed. In the control group, the two-stage ear reconstruction using the postauricular fascial flap was performed. The patients were followed regularly after the surgery, and the surgical effect, satisfaction rate, incidence of complications of the two groups were evaluated. Results Statistical analysis showed that there were no statistically significant differences between the experimental group and the control group in terms of postoperative satisfaction, postoperative complication rate of skin problems and surgical effect (P>0.05), but the incidence of postoperative scar was significantly different between the two groups (P<0.05). Conclusion The three-stage auricular reconstruction surgery with retained superficial temporal fascia shows good postoperative effect, and the scar is not obvious, which is worthy of clinical application. Figures and Tables | References | Related Articles | Metrics

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Effect of Exosomes Derived from Septic Rats on Immunoregulation of WJ-MSC Junyan FANG, Ahui SONG, Yan TONG, Feng DING, Yingli LIU 2020, 16 (3):  223-229.  DOI: 10.3969/j.issn.1673-0364.2020.03.013 Abstract ( 471 )   HTML ( 26 )   PDF (2537KB) ( 209 )   Objective To explore the effect of peripheral blood exosomes from sepsis rats on the immune characteristics of human umbilical cord Wharton's jelly-derived mesenchymal stem cells (WJ-MSC). Methods The sepsis rat model was established by means of cecal perforation ligation (CLP). Exosomes from peripheral blood of rats in the control group (sham operation group) and experimental group (CLP model group) were extracted to identify their surface markers and morphological characteristics, and pretreated to WJ-MSC. Cell activity of WJ-MSC was detected by CCK8, apoptosis of WJ-MSC was detected by Annexin V-FITC/PI, and qPCR was used to detect the mRNA levels of cytokines (IL-10, TNF-α). The pretreated WJ-MSC was co-cultured with human mononuclear macrophages cells (THP-1) stimulated by LPS, and the mRNA expression of cytokines (IL-6, lL-10, TNF-α, IL-1β) of THP-1 cells was detected by qPCR. Results There was no significant difference in surface markers and morphological characteristics between the exosomes of experimental and control group. Exosomes of experimental group could not affect the proliferation of WJ-MSC, but inhibited its apoptosis, promoted the mRNA level of IL-10, and reduced the mRNA level of TNF-α. WJ-MSC pretreated by two kinds of exosomes could reduce the expression of pro-inflammatory cytokines (IL-1β,TNF-α) of LPS-stimulated THP-1 cells, but there was no significant difference between the two groups. Conclusion Exosomes from peripheral blood of sepsis rats can up-regulate the expression of IL-10 in WJ-MSC and down-regulate the expression of TNF-α, which may enhance its immune regulation ability. Figures and Tables | References | Related Articles | Metrics

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Feasibility Study of Quantitative Analysis of Survival Rate of Facial Fat Graft by CT Tomography Haizhen WANG, Fei DING, Yafang WANG, Beiyong ZHAO, Guozhang MAO 2020, 16 (3):  229-231.  DOI: 10.3969/j.issn.1673-0364.2020.03.014 Abstract ( 517 )   HTML ( 20 )   PDF (1104KB) ( 192 )   Objective To explore the feasibility of quantitative analysis of survival rate of facial fat graft by CT tomography. Methods From December 2015 to March 2016, 8 patients who underwent facial fat filling were included in the study. Facial CT scan was performed before, 4 weeks and 12 weeks after surgery, respectively. Then the area of grafted fat tissue (regions of interest, ROI) was measured and statistically analyzed, and relative value of fat survival was calculated. Results CT tomography imaging can clearly show the level of fat in the filling area of the face. The ROI of fat transplantation area before, 4 weeks and 12 weeks after surgery was 4.61±1.32, 9.17±2.01 and 7.60±1.47, respectively. Statistical result showed that ROI at 12 weeks and 4 weeks after surgery were both significantly higher than that before surgery (P<0.05), but ROI at 12 weeks and 4 weeks after surgery showed no significant difference (P>0.05). Compared with 4 weeks after surgery, the survival value of transplanted fat at 12 weeks after surgery was 65.57%±10.27%. Conclusion The technique of CT tomography imaging can be used as a method of quantitative analysis for survival rate of facial fat graft. Figures and Tables | References | Related Articles | Metrics

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Evaluation of Three Kinds of Skin Repair Materials on the Effectiveness of Skin Injury Repair in Diabetic Rats Qianqian HAN, Mingyue QU, Bin XUE, Chunren WANG 2020, 16 (3):  232-236.  DOI: 10.3969/j.issn.1673-0364.2020.03.015 Abstract ( 603 )   HTML ( 60 )   PDF (1701KB) ( 330 )   Objective To evaluate the effectiveness of collagen, carboxymethyl chitosan and gelatin bioactive glass in repairing the skin injury of diabetic rats. Methods The best skin injury model of diabetic rats was established by injecting different concentration of STZ solution in single time and excising the whole skin of different sizes in the back of SD male rats respectively. Three kinds of skin dressings were attached directly to the injured area and covered with sterile dressings in order to promote skin healing. The general wound recovery was observed and wound healing rate of each group was calculated. HE staining was used to observe the recovery of wound in different periods. Results A single intraperitoneal injection of 75 mg/Kg STZ solution and the construction of 2 cm×2 cm back skin injury could establish the best skin injury model of diabetic rats. Collagen and gelatin bioactive glass promoted skin healing to a certain extent, and the healing rate was statistically different from the blank control. Conclusion Collagen and gelatin bioactive glass have therapeutic effect on skin injury of diabetic rats, carboxymethyl chitosan only has hemostatic effect in early stage. Figures and Tables | References | Related Articles | Metrics

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Regeneration of Degenerated Intervertebral Disc with Autologous Bone Marrow Mononuclear Cells in Rabbit Models Jihao CUI, Chuang LI, Wenbin MA, Chun LI, Wanhong XU 2020, 16 (3):  237-240.  DOI: 10.3969/j.issn.1673-0364.2020.03.016 Abstract ( 361 )   HTML ( 45 )   PDF (1232KB) ( 188 )   Objective To investigate the regenerative effect of autologous bone marrow mononuclear cells on degenerated intervertebral disc in rabbit models. Methods A total of 12 New Zealand white rabbits were selected. The rabbits were randomly divided into two groups: the control group (n=6) and the treatment group (n=6). Bone marrow was extracted from the posterior superior iliac spine of the New Zealand white rabbit, and autologous bone marrow mononuclear cells were extracted by density gradient centrifugation. L4/5, L5/6 and L6/7 intervertebral disc puncture models were made with 16 G needle after anesthesia in the two groups of rabbits. Autologous bone marrow mononuclear cells were injected into the punctured disc of the treatment group and no treatment was done in the control group. Then the rabbits in the two groups were raised under the same conditions. Imaging (X-ray and MR) and histological observation of the disc were performed at weeks 4, 8, and 24, respectively. Results In terms of maintaining the height of intervertebral space, the treatment group was superior to the control group as the number of weeks increased. In terms of signal strength of MR T2W1 and histological morphology, the treatment group was significantly better than that of the control group. Histological observation showed that compared with the treatment group, the number of nucleus pulposus cells in the control group was reduced, and the extracellular matrix was contracted and uneven. Conclusion Bone marrow monoculear cells transplantation can regenerate the degenerated intervertebral disc in rabbit models. Figures and Tables | References | Related Articles | Metrics

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Analysis of Physical Activity Level and its Influencing Factors in Patients after Total Knee Arthroplasty Jianxian YU, Kaiyun ZHOU 2020, 16 (3):  241-244.  DOI: 10.3969/j.issn.1673-0364.2020.03.017 Abstract ( 433 )   HTML ( 20 )   PDF (705KB) ( 204 )   Objective To investigate the physical activity level and its influencing factors in patients after total knee arthroplasty. Methods The subjects were recruited according to the inclusion and exclusion criteria by simple random sampling method, and "General data questionnaire", "International Physical Activity Questionnaire", "Regulation Questionnaire of Physical activity" and "hospital for Special surgery knee score" were adopted to investigate in this study. Results A total of 112 patients participated in the study. The total average physical activity was (5 087.39±2 234.21), and the low, medium, and high intensity activities were (1 612.89±340.89), (1 009.31±818.23), (267.76±49.89) respectively. The motivation for physical activity was (41.89±11.78), of which the autonomic motivation score was (29.18±8.87), the external adjustment score was (6.59±2.01), the endoscopic adjustment score was (5.43±1.48). The knee joint function assessment score was (71.33±13.01). The age, BMI, knee joint function, physical activity motivation, condition of residence all affected physical activity level (P<0.01). Conclusion The physical activity level of patients after total knee arthroplasty is low. Age, BMI, knee joint function, physical activity motivation, condition of residence are positive factors of physical activity level. References | Related Articles | Metrics

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Preparation and Evaluation of Psychological Resilience Assessment Tool for Adolescent Patients Undergoing Neck Scar Resection and Skin Grafting Ying HUANG, Weiwei BIAN 2020, 16 (3):  245-249.  DOI: 10.3969/j.issn.1673-0364.2020.03.018 Abstract ( 345 )   HTML ( 47 )   PDF (775KB) ( 180 )   Objective To develop a psychological resilience scale for adolescents with severe neck scar. Methods Scale item pools were constructed through literature search and patient interviews. Delphi expert consultation method, item analysis, coefficient of variation, item-item correlation coefficient, item-dimension correlation coefficient, internal consistency coefficient, factor analysis were applied. The items were screened and the reliability and validity were checked. Results Six principal factors were extracted through principal component factor analysis. The relationship between the distribution and dimensions of the common factors was basically consistent with the oretical framework of "Kumper's Psychological Elasticity". The correlation coefficient between dimensions of the scale was 0.402-0.691, and the correlation between dimensions was statistically significant (P<0.01). The correlation coefficient between dimensions and the total score was 0.701-0.832, and the correlation between dimensions and the total score was statistically significant (P<0.01). The total Cronbach's α coefficient of this scale was 0.872, indicating good reliability. Conclusion The formed psychological resilience scale for adolescents with severe neck scar has good reliability and validity, and it can be widely used in the assessment of psychological resilience for adolescents undergoing neck scar resection and skin grafting. Figures and Tables | References | Related Articles | Metrics

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Effect of Continuous Nursing Care Based on WeChat Platform on Postoperative Efficacy of Lumbar Fusion Yihong YU, Jie YANG, Ling ZHOU 2020, 16 (3):  250-252.  DOI: 10.3969/j.issn.1673-0364.2020.03.019 Abstract ( 307 )   HTML ( 17 )   PDF (696KB) ( 199 )   Objective To evaluate the clinical effectiveness of continuous nursing care based on WeChat platform on postoperative efficacy of lumbar fusion. A total of 80 patients underwent posterior lumbar fusion were included, which were randomly divided into the observation group and the control group. Routine discharge education and telephone follow-up were carried out in the control group. Besides the routine education and telephone follow-up, the patients in the observation group were given continuous nursing care after discharge based on WeChat platform. The satisfaction rate, Visual Analogue Scale (VAS), Japanese Orthopaedic Association Scores (JOA) and JOA recovery rate were compared between the two groups. Results The mean follow-up was 14.3 months. At the final follow-up, the satisfaction rate of the observation group was 92.5%, significantly higher than that of the control group (75.0%,P<0.05). Three days after the operation, there was no significant difference in VAS and JOA scores between the two groups (P>0.05). However, from 3 months to 1 year after the operation, the VAS and JOA scores of the observation group were significantly higher than those of the control group (P<0.05). One year after the operation, the recovery rate of JOA in the observation group was 85.0%, significantly higher than that of the control group (62.5%, P<0.05). Conclusion Continuous nursing based on WeChat platform can improve the satisfaction rate of patients after posterior lumbar fusion, promote postoperative functional recovery and improve the clinical effectiveness. References | Related Articles | Metrics

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Research Progress of the Treatment for the Lower Palpebral Bags with Tear Trough Deformity Zhen SONG, Qinghua YANG 2020, 16 (3):  253-256.  DOI: 10.3969/j.issn.1673-0364.2020.03.020 Abstract ( 357 )   HTML ( 39 )   PDF (706KB) ( 471 )   The lower palpebral bags with tear trough deformity has different degrees of influence on the facial appearance and mental health of the patient. The lower eyelid blepharoplasty has been developed in the last century, and the concept and method of blepharoplasty for the lower palpebral bags with tear trough deformity have been continuously developed. In addition to surgical treatment, other treatments such as laser treatment, autologous fat transplantation, hyaluronic acid and other substances injections have their own advantages and characteristics, and have achieved good result. In this paper, the progress of the treatment for the lower palpebral bags with tear trough deformity was reviewed. References | Related Articles | Metrics

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Classification of Nasal Alar Hypertrophy and Progress in Clinical Treatment Zongqin PAN, 2020, 16 (3):  257-259.  DOI: 10.3969/j.issn.1673-0364.2020.03.021 Abstract ( 461 )   HTML ( 31 )   PDF (692KB) ( 332 )   Nasal alar hypertrophy is a group of clinical manifestations including wide nasal base, hypertrophy and expansion of the nasal alar. At present, the main treatments of nasal alar hypertrophy are embedding suture and tissue resection. In this paper, the alar hypertrophy was classified according to the different clinical manifestations of alar hypertrophy and its clinical treatment progress was reviewed. References | Related Articles | Metrics

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Research Progress of Hair Transplantation Technique in Hairline Reconstruction Jun ZHAO, Zhentao ZHOU, Weili XU, Yue ZHOU, Jufang ZHANG 2020, 16 (3):  260-262.  DOI: 10.3969/j.issn.1673-0364.2020.03.022 Abstract ( 390 )   HTML ( 51 )   PDF (752KB) ( 229 )   Hairline has an important effect on facial beauty. There are a variety of known diseases and innate factors that can cause defects in the hairline. In recent years, hair transplantation technology in hairline reconstruction has made a great progress, but there are also some problems. In this paper, the research progress of hair transplantation technique in hairline reconstruction was reviewed. References | Related Articles | Metrics