Abstract: As the top tensioned risers (TTRs) are intensively arranged in the wellhead zone in the platform, the interference analysis between TTRs is one of the most important engineering design parts. Interference sensitivity analysis is carried out based on the TTRs in a tension leg platform (TLP), and the interference results with different top tensions, riser spaces, TLP offsets and TLP movements are compared. The analysis results show that the top tension and TLP offset have the major impact on the interference analysis, and the quasi-static interference analysis can reflect the interference phenomenon, the dynamic analysis is not necessary in the early design stage, which can reduce the engineering design works.