7 381例孕妇产前不规则抗体检测特异性分析及临床意义

doi:10.16150/j.1671-2870.2019.03.023

诊断学理论与实践 ›› 2019, Vol. 18 ›› Issue (03): 365-367.doi: 10.16150/j.1671-2870.2019.03.023

7 381例孕妇产前不规则抗体检测特异性分析及临床意义

孙文瑾, 王淑平, 汤伟娴, 陈慧芬()

同济大学附属第一妇婴保健院检验科,上海 200040

收稿日期:2019-01-24 出版日期:2019-06-25 发布日期:2019-06-25
通讯作者: 陈慧芬 E-mail:chenhuifen@51mch.com

The clinical significance of screening irregular blood group antibodies and detecting its specificity in pregnant women

SUN Wenjin, WANG Shuping, TANG Weixian, CHEN Huifen()

Clinical Laboratory, The First Maternity and Infant Hospital Affiliated to Tongji Universit, Shanghai 200040, China

Received:2019-01-24 Online:2019-06-25 Published:2019-06-25
Contact: CHEN Huifen E-mail:chenhuifen@51mch.com

摘要/Abstract

摘要：

目的： 对在我院产检的孕妇进行血型不规则抗体筛查和抗体特异性检测,了解孕妇不规则抗体的检出情况及相关临床特征。方法： 采用微柱凝胶卡,对2017年1月至2018年8月来我院产检的孕妇进行血型不规则抗体筛查,并对筛查阳性的标本进行抗体特异性鉴定分析。结果： 7 381名孕妇中,32例检出不规则抗体,阳性率为0.434%,其中抗M 10例、抗E 3例、抗Ec 8例、抗D 4例、抗Lea 4例、抗Dia 1例、抗Wra 1例、冷抗体1例。以上检出不规则抗体的孕妇均具有1次以上的妊娠史。结论： 本院孕妇的血型不规则抗体检出率为0.434%,其中抗M最多见。

关键词: 血型不规则抗体, 新生儿溶血病, 溶血性输血反应

Abstract:

Objective: To screen irregular blood group antibodies and detecte its specificity in pregnant women for exploring the presence of irregular antibodies and related clinical characteristics. Method: Microcolumn gel card was used to screen irregular blood group antibodies in pregnant women undergoing maternal examination in our hospital from January 2017 to August 2018 and analyzing the antibody specificity of positive screening specimens. Results: Of the 7 381 pregnant women, 32 had irregular blood group antibodies detected,the positive rate was 0.434%. Among them, 10 cases were anti-M, 3 cases were anti-E, 8 cases were anti-Ec, 4 cases were anti-D, 4 cases were anti-Lea, 1 case was anti-Dia, 1 case was anti-Wra,1 case was cold antibody. The pregnant women who had irregular blood group antibodies detected all had more than one pregnancy history. Conclusions: The irregular blood group antibodies detection rate was 0.434% in pregnant women taking maternal examination at our hospital; anti-M was the most frequent. The antibodies of Rh blood group system and MNS blood group system could lead to the occurrence of hemolysis disease in newborn infants.

Key words: Irregular blood group antibody, Hemolytic disease of newborn, Hemolytic transfusion reaction

中图分类号:

R556.6

孙文瑾, 王淑平, 汤伟娴, 陈慧芬. 7 381例孕妇产前不规则抗体检测特异性分析及临床意义[J]. 诊断学理论与实践, 2019, 18(03): 365-367.

SUN Wenjin, WANG Shuping, TANG Weixian, CHEN Huifen. The clinical significance of screening irregular blood group antibodies and detecting its specificity in pregnant women[J]. Journal of Diagnostics Concepts & Practice, 2019, 18(03): 365-367.

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7 381例孕妇产前不规则抗体检测特异性分析及临床意义

The clinical significance of screening irregular blood group antibodies and detecting its specificity in pregnant women

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