Journal of Diagnostics Concepts & Practice ›› 2021, Vol. 20 ›› Issue (02): 161-167.doi: 10.16150/j.1671-2870.2021.02.008
• Original articles • Previous Articles Next Articles
QIAN Le, JIANG Meijiao, YANG Bowen, CHEN Hui()
Received:
2021-01-29
Online:
2021-04-25
Published:
2022-06-28
Contact:
CHEN Hui
E-mail:ch11516@rjh.com.cn
CLC Number:
QIAN Le, JIANG Meijiao, YANG Bowen, CHEN Hui. The ultrasonic features and diagnostic performance of ultrasound for ovarian cystadenofibroma and adenofibroma[J]. Journal of Diagnostics Concepts & Practice, 2021, 20(02): 161-167.
特征 | 良性CAF (46例) | AF (7例) | 交界性CAF (4例) |
---|---|---|---|
年龄(岁) | 48(33.3~58.0) | 48(45.0~56.0) | 38.5(29.0~56.0) |
既往卵巢手术史 | 3(6.5%) | 1 | 0 |
卵巢癌家族史或个人史 | 0/0 | 0/0 | 0/0 |
已绝经/未绝经 | 19/27 | 3/4 | 1/3 |
临床症状 | |||
腹痛、腹胀、腹围增大 | 10(21.7%) | 0 | 0 |
腹部触及包块 | 10(21.7%) | 2 | 0 |
阴道异常出血 | 2(4.3%) | 1 | 0 |
体重明显改变 | 2(4.3%) | 1 | 0 |
无明显症状 | 22(47.8%) | 3 | 4 |
肿瘤指标 CA12-5>35 U/mL [n(%)] | 5(10.9%) | 0 | 1 |
CA12-5(U/mL) | 12.3(10.1~18.7) | 9.7(9.1~10.8) | 21.2(15.7~205.1) |
HE4>60.5 U/mL [n(%)] | 7(15.2%) | 0 | 0 |
HE4(U/mL) | 38.0(32.9~47.1) | 44.0(40.1~46.7) | 41.2(36.0~43.1) |
特征 | 良性CAF(n=47) | AF(n=7) | 交界性CAF(n=4) |
---|---|---|---|
肿块位置 | |||
卵巢内 | 9(19.1%) | 2 | 1 |
卵巢旁 | 16(34.0%) | 2 | 1 |
无法辨别 | 22(46.8%) | 3 | 2 |
肿块最大径(mm) | 47(31~85) | 33(24~70) | 54.5(45~96) |
肿块形态规则 | 43(91.5%) | 6 | 2 |
肿块边界清晰 | 46(97.9) | 5 | 2 |
肿块分类 | |||
单房囊性 | 4(8.5%) | 0 | 0 |
单房囊实性 | 25(53.2%) | 2 | 1 |
实性 | 2(4.3%) | 4 | 1 |
多房囊性 | 8(17.0%) | 1 | 0 |
多房囊实性 | 8(17.0%) | 0 | 2 |
分隔厚度(mm) | 2.3(1.9~3.3) | 1.3 | 1.3/3.7 |
实性部分或乳头状突起 | 35(74.5%) | 6 | 4 |
实性部分或乳头状突起最大径(mm) | 8.0(7.0~13.0) | 18.5(9.3~30.8) | 19.5(18.8~26.3)a) |
实性部分或乳头状突起/肿块最大径比值 | 0.15(0.12~0.25) | 1.00(0.46~1.00) | 0.35(0.30~0.52)b) |
乳头状突起 | 32(68.1%) | 2 | 3 |
1枚 | 13/32(40.6%) | 0/2 | 0/3 |
2枚 | 3/32(9.4%) | 0/2 | 0/3 |
3枚 | 5/32(15.6%) | 1/2 | 0/3 |
≥4枚 | 11/32(34.4%) | 1/2 | 3/3 |
乳头状突起最大径(mm) | 7.5(7.0~11.3) | 8/8 | 6/19/20 |
乳头状突起最大径/肿块最大径比值 | 0.15(0.12~0.22) | 0.11,0.29 | 0.11,0.20,0.36 |
实性部分或乳头状突起血流评分 | |||
1分(无) | 25/35(71.4%) | 6/6 | 0/4c) |
2分(少量) | 8/35(22.9%) | 0/6 | 1/4 |
3分(中等) | 2/35(5.7%) | 0/6 | 2/4 |
4分(丰富) | 0/35(0) | 0/6 | 1/4 |
实性部分或乳头状突起后方回声衰减 | 15(31.9%) | 4 | 1 |
肿块后方回声增强 | 27(57.4%) | 3 | 2 |
[1] |
Taylor EC, Irshaid L, Mathur M. Multimodality imaging approach to ovarian neoplasms with pathologic correlation[J]. Radiographics, 2021, 41(1):289-315.
doi: 10.1148/rg.2021200086 pmid: 33186060 |
[2] |
Cho SM, Byun JY, Rha SE, et al. CT and MRI findings of cystadenofibromas of the ovary[J]. Eur Radiol, 2004, 14(5):798-804.
doi: 10.1007/s00330-003-2060-z URL |
[3] |
Czernobilsky B, Borenstein R, Lancet M. Cystadenofibroma of the ovary. A clinicopathologic study of 34 cases and comparison with serous cystadenoma[J]. Cancer, 1974, 34(6):1971-1981.
pmid: 4434327 |
[4] |
Kozawa E, Inoue K, Takahashi M, et al. Diffusion-weighted MR imaging findings of ovarian adenocarcinofibromas and adenofibromas[J]. Clin Imaging, 2014, 38(4):483-489.
doi: 10.1016/j.clinimag.2014.01.014 URL |
[5] |
Timmerman D, Valentin L, Bourne TH, et al. Terms, de-finitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis(IOTA) Group[J]. Ultrasound Obstet Gynecol, 2000, 16(5):500-505.
doi: 10.1046/j.1469-0705.2000.00287.x URL |
[6] |
Andreotti RF, Timmerman D, Strachowski LM, et al. ORADS US risk stratification and management system: a consensus guideline from the ACR Ovarian-Adnexal Reporting and Data System Committee[J]. Radiology, 2020, 294(1):168-185.
doi: 10.1148/radiol.2019191150 pmid: 31687921 |
[7] |
Tang YZ, Liyanage S, Narayanan P, et al. The MRI features of histologically proven ovarian cystadenofibromas-an assessment of the morphological and enhancement patterns[J]. Eur Radiol, 2013, 23(1):48-56.
doi: 10.1007/s00330-012-2568-1 pmid: 22814827 |
[8] | 潘玉萍, 蔡爱露, 赵丹, 等. 卵巢腺纤维瘤及囊性腺纤维瘤的超声特征[J]. 中国医学影像技术, 2012, 28(9):1699-1701. |
[9] |
Shimizu S, Okano H, Ishitani K, et al. Ovarian cystadenofibroma with solid nodular components masqueraded as ovarian cancer[J]. Arch Gynecol Obstet, 2009, 279(5):709-711.
doi: 10.1007/s00404-008-0785-2 pmid: 18779972 |
[10] | 徐健, 梅海炳, 高军, 等. 卵巢浆液性囊性腺纤维瘤MR诊断及病理分析[J]. 医学影像学杂志, 2016, 26(8):1494-1497. |
[11] |
Virgilio BA, de Blasis I, Sladkevicius P, et al. Imaging in gynecological disease(16): clinical and ultrasound cha-racteristics of serous cystadenofibromas in adnexa[J]. Ultrasound Obstet Gynecol, 2019, 54(6):823-830.
doi: 10.1002/uog.20277 pmid: 30937992 |
[12] |
Goldstein SR, Timor-Tritsch IE, Monteagudo A, et al. Cystadenofibromas: can transvaginal ultrasound appea-rance reduce some surgical interventions?[J]. J Clin Ultrasound, 2015, 43(6):393-396.
doi: 10.1002/jcu.22241 pmid: 25271400 |
[13] |
Landolfo C, Valentin L, Franchi D, et al. Differences in ultrasound features of papillations in unilocular-solid adnexal cysts: a retrospective international multicenter study[J]. Ultrasound Obstet Gynecol, 2018, 52(2):269-278.
doi: 10.1002/uog.18951 pmid: 29119698 |
[14] |
Timor-Tritsch IE, Yoon E, Monteagudo A, et al. Ultrasound and histopathologic correlation of ovarian cystadenofibromas: diagnostic value of the “shadow sign”[J]. J Ultrasound Med, 2019, 38(11):2973-2978.
doi: 10.1002/jum.15003 pmid: 30927305 |
[15] |
Zheng X, Lyu G, Gan Y, et al. Microcystic pattern and shadowing are independent predictors of ovarian borderline tumors and cystadenofibromas in ultrasound[J]. Eur Radiol, 2021, 31(1):45-54.
doi: 10.1007/s00330-020-07113-z URL |
[16] |
Takeuchi M, Matsuzaki K, Harada M. Ovarian adenofibromas and cystadenofibromas: magnetic resonance ima-ging findings including diffusion-weighted imaging[J]. Acta Radiol, 2013, 54(2):231-236.
doi: 10.1258/ar.2012.120516 pmid: 23171527 |
[17] |
Jung DC, Kim SH, Kim SH. MR imaging findings of ovarian cystadenofibroma and cystadenocarcinofibroma: clues for the differential diagnosis[J]. Korean J Radiol, 2006, 7(3):199-204.
doi: 10.3348/kjr.2006.7.3.199 URL |
[18] | 顾海磊, 唐文伟, 田忠甫, 等. 卵巢(囊)腺纤维瘤的磁共振成像诊断及鉴别[J]. 实用放射学杂志, 2020, 36(11):1798-1801. |
[19] |
Chen H, Liu Y, Shen LF, et al. Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison[J]. J Ovarian Res, 2016, 9(1):81.
pmid: 27876070 |
[20] |
Zhang Z, Wu Y, Gao J. CT diagnosis in the thecoma-fibroma group of the ovarian stromal tumors[J]. Cell Biochem Biophys, 2015, 71(2):937-943.
doi: 10.1007/s12013-014-0288-7 URL |
[21] | 张慧娟. 卵巢交界性腺纤维瘤及囊腺纤维瘤的病理诊断[J]. 实用妇产科杂志, 2005, 21(10):586-588. |
[1] | WANG Wenhan, XIA Shujun, ZHAN Weiwei. Application of long non-coding RNA ENST00000489676 detection in ultrasonographic evaluation of cervical lymph node metastasis in papillary thyroid carcinoma [J]. Journal of Diagnostics Concepts & Practice, 2022, 21(04): 514-519. |
[2] | XU Chenying, LI Yanran, NI Xiaofeng, XU Shangyan, LIN Qing. Efficacy of ultrasonic examination in predicting cervical lymph node metastasis in elderly patients with papillary thyroid carcinoma and analysis of related ultrasound signs [J]. Journal of Diagnostics Concepts & Practice, 2022, 21(03): 343-348. |
[3] | YANG Bowen, JIANG Meijiao, CHEN Hui. Study on differential diagnosis of malignant and benign ovarian tumors through IOTA simple rules [J]. Journal of Diagnostics Concepts & Practice, 2022, 21(01): 74-79. |
[4] | HE Biyuan, ZHOU Yuqing, YAO Bingyi, CAO Li, BAO Li. The clinical value of intelligent quantitative measurement of cervical elastography in predicting spontaneous preterm birth during second trimester [J]. Journal of Diagnostics Concepts & Practice, 2021, 20(05): 450-455. |
[5] | YANG Yixian, NI Zhongxin, XIA Shujun, ZHOU Wei, ZHAN Weiwei. A comparison of clinicopathologic and ultrasonic features between unifocal and multifocal papillary thyroid carcinoma [J]. Journal of Diagnostics Concepts & Practice, 2021, 20(02): 168-172. |
[6] | YAN Bing, WANG Haifei, CAO Yunyun, NIU Jianmei. Comparative analysis of ultrasonographic features and clinicopathological types for mucinous breast carcinoma and analysis of the causes for misdiagnosis [J]. Journal of Diagnostics Concepts & Practice, 2020, 19(04): 386-390. |
[7] | WANG Yan, ZHANG Jingwen, ZHAN Weiwei. High frequency ultrasound in combination with dynamic tests in diagnosis of pharyngoesophageal diverticulum [J]. Journal of Diagnostics Concepts & Practice, 2020, 19(03): 264-268. |
[8] | GU Yaoyao, NI Xuejun. Clinical value of ultrasonography in diagnosis of cervical lymph node metastasis of thyroid cancer [J]. Journal of Diagnostics Concepts & Practice, 2019, 18(06): 662-667. |
[9] | YANG Minmin, LIU Min, CHEN Yan, HE Suhui, ZHENG Liya. Diagnostic efficiency of transvaginal ultrasound four-dimensional contrast hysterosalpingography in evaluation of fallopian tube patency and analysis of misdiagnosed cases [J]. Journal of Diagnostics Concepts & Practice, 2018, 17(02): 202-206. |
[10] | CHEN Hui, GUO Qianhui, XU Jie, CHENG Yibang, ZHANG Dongyan, WANG Ying, HUANG Qifang, SHENG Changsheng, LI Yan. Prevalence and determinants of asymptomatic intracranial artery stenosis assessed by transcranial Doppler ultrosonography [J]. Journal of Diagnostics Concepts & Practice, 2017, 16(06): 592-595. |
[11] | LI Junwei, XIA Hanbing, ZHAO Hongli, LIU Shuxia. Predictive value of epicardial adipose tissue thickness detected by ultrasonography for coronary artery disease [J]. Journal of Diagnostics Concepts & Practice, 2017, 16(03): 324-327. |
[12] | YANG Zexuan, ZHOU Liuying, DENG Ying. Clinical value of prenatal ultrasonography in diagnosis of fetal hepatic space occupying lesion [J]. Journal of Diagnostics Concepts & Practice, 2017, 16(02): 204-207. |
[13] | JIANG Meijiao, ZHAN Weiwei, CHEN Hui, XU Ruiyun, YANG Zhifang, LIU juan. Misdiagnosis of low position intestinal tumors in women by ultrasonography [J]. Journal of Diagnostics Concepts & Practice, 2017, 16(01): 109-113. |
[14] | KANG Huili, DONG Yijie, ZHAN Weiwei. Relevant factor analysis of cervical lymph nodes metastasis in papillary thyroid microcarcinoma [J]. Journal of Diagnostics Concepts & Practice, 2016, 15(05): 482-486. |
[15] | . [J]. Journal of Diagnostics Concepts & Practice, 2016, 15(02): 165-168. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||