Report of a case of composite pheochromocytoma and review of literature

doi:10.16150/j.1671-2870.2019.02.009

Abstract

Abstract:

Objective: To study the clinicopathological characteristics and immunotype of composite pheochromocytoma-ganglioneuroma (CP-GN). Methods: The clinicopathological features of one CP-GN patient were analyzed by HE and immunochemistry staining，and related literatures were reviewed. Result: The patient was a male with adrenal mass. Pathological examination revealed that the tumor consisted of two components: the first component was pheochromocytoma,tumor cells were arranged in nests with basophilic or amphiphilic cytoplasm; the other component was ganglioneuroma, the ganglion cells were scattered in the background of the bundle and braided schwann cells. Both CgA and Syn were strongly and diffusely positive in the pheochromocytoma, while staining for S100 protein and NF identified Schwann cells and ganglion cells were observed in the ganglioneuroma. The Ki-67 index was low in CP-GN. Conclusions: CP-GN is rare, and its histological structure is mixed. Patient has better prognosis after operation.

Key words: Adrenal gland neoplasms, Composite Pheochromocytoma, Immunohistochemistry

CLC Number:

R586

JIN Jiaoying, LI Qianyu, JIANG Hongwei, HAN Dongyan, XI Hao, WEI Qing. Report of a case of composite pheochromocytoma and review of literature[J]. Journal of Diagnostics Concepts & Practice, 2019, 18(2): 165-169.

Figures/Tables 2

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