Journal of Internal Medicine Concepts & Practice ›› 2021, Vol. 16 ›› Issue (02): 97-102.doi: 10.16138/j.1673-6087.2021.02.007
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XU Lei, XU Yiming, SHEN Honghua, ZHANG Yin, REN Lei()
Received:
2020-10-30
Online:
2021-04-25
Published:
2022-07-26
Contact:
REN Lei
E-mail:JALNRL928@163.com
CLC Number:
XU Lei, XU Yiming, SHEN Honghua, ZHANG Yin, REN Lei. The impact of comorbidity of stroke and obstructive sleep-hypopnea apnea on sleep, cognition and nerve function[J]. Journal of Internal Medicine Concepts & Practice, 2021, 16(02): 97-102.
项目 | OSAHS组(n=70) | 卒中组 (n=98) | 卒中合并OSAHS组(n=228) | χ2/F | P |
---|---|---|---|---|---|
男性[n(%)] | 42(60.0) | 47(48.0) | 134(58.8) | 3.727 | 0.155 |
年龄(岁) | 67.4±7.8 | 69.2±11.1 | 68.4±8.1 | 0.868 | 0.421 |
BMI(kg/m2) | 24.0±3.4 | 20.8±2.31) | 21.1±2.41) | 40.253 | <0.001 |
受教育年限(年) | 9.5±2.6 | 9.6±2.9 | 10.2±2.8 | 2.462 | 0.087 |
MMSE(分) | 25.1±3.0 | 21.2±4.71) | 20.0±5.61) | 27.516 | <0.001 |
吸烟[n(%)] | 23(32.9) | 36(36.7) | 98(43.0) | 2.756 | 0.252 |
饮酒[n(%)] | 24(34.3) | 25(25.5) | 87(38.2) | 4.862 | 0.088 |
基础疾病[n(%)] | |||||
高血压 | 45(64.3) | 62(63.3) | 190(83.3)1)2) | 19.927 | <0.001 |
2型糖尿病 | 32(45.7) | 46(46.9) | 148(64.9)1)2) | 13.513 | 0.001 |
冠心病 | 36(51.4) | 60(61.2) | 161(70.6)1)2) | 9.426 | 0.009 |
高脂血症 | 29(27.1) | 19(19.4) | 67(29.4) | 3.534 | 0.171 |
房颤 | 2(2.9) | 5(5.1) | 27(11.8)1)2) | 7.523 | 0.023 |
项目 | 卒中组(n=98) | OSAHS合并卒 中组(n=228) | χ2 | P |
---|---|---|---|---|
初次卒中 | 71(72.4) | 89(39.0) | 30.620 | <0.001 |
再次卒中 | 27(27.6) | 139(61.0) | ||
卒中性质 | 2.639 | 0.267 | ||
蛛网膜下腔出血 | 5(5.1) | 21(9.2) | ||
脑出血 | 20(20.4) | 56(24.6) | ||
脑梗死 | 73(74.5) | 151(66.2) | ||
卒中病程 | 3.719 | 0.156 | ||
短暂性脑缺血 | 6(6.1) | 27(11.8) | ||
进展性卒中 | 23(23.5) | 63(27.6) | ||
完全性卒中 | 69(70.4) | 138(60.5) | ||
病变部位 | 8.643 | 0.279 | ||
脑干 | 2(1.6) | 10(3.3) | ||
小脑 | 2(1.6) | 5(1.7) | ||
间脑 | 5(3.9) | 18(6.0) | ||
大脑基底核 | 49(38.0) | 138(45.8) | ||
额叶 | 27(20.9) | 61(20.3) | ||
颞叶 | 19(14.7) | 36(12.0) | ||
顶叶 | 16(12.4) | 19(6.3) | ||
枕叶 | 9(7.0) | 14(4.7) |
参数 | 卒中合并轻度OSAHS组(n=111) | 卒中合并中度OSAHS组(n=64) | 卒中合并重度OSAHS组(n=53) | χ2/F | P |
---|---|---|---|---|---|
男性[n(%)] | 63(56.8) | 39(60.9) | 32(60.4) | 0.366 | 0.838 |
FMA(分) | 56.3±10.9 | 52.8±10.1 | 49.5±11.51) | 7.389 | 0.001 |
NIHSS(分) | 10.1±2.8 | 11.1±2.61) | 11.3±2.61) | 4.554 | 0.012 |
BI(分) | 61.0±15.0 | 59.2±15.0 | 52.8±15.61)2) | 5.485 | 0.005 |
BMI(kg/m2) | 20.9±2.3 | 21.0±2.4 | 21.5±2.4 | 1.257 | 0.286 |
MMSE(分) | 21.7±4.7 | 19.3±6.21) | 17.5±5.41)2) | 11.993 | <0.001 |
AHI(次/h) | 10.6±3.0 | 25.7±2.21) | 38.1±5.51)2) | 1 130.111 | <0.001 |
L-SaO2(%) | 85.1±7.1 | 82.4±6.71) | 77.3±6.31)2) | 24.031 | <0.001 |
TS90(%) | 2.1±1.8 | 2.4±1.21) | 2.9±1.51) | 4.604 | 0.011 |
MAI | 18.5±7.8 | 28.7±19.31) | 40.9±20.91)2) | 39.092 | <0.001 |
NREM 1(%) | 45.7±12.0 | 57.0±6.21) | 65.1±4.71)2) | 84.634 | <0.001 |
NREM 2(%) | 31.7±12.4 | 26.8±8.11) | 26.4±6.11) | 7.313 | 0.001 |
NREM 3(%) | 12.6±2.6 | 6.7±2.01) | 3.6±2.21)2) | 301.571 | <0.001 |
REM(%) | 10.0±2.5 | 9.6±3.9 | 4.9±4.01)2) | 43.664 | <0.001 |
ESS(分) | 10.8±3.0 | 12.7±3.81) | 18.3±3.61)2) | 90.256 | <0.001 |
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