Research progress on prognostic biomarkers for colorectal cancer

doi:10.16138/j.1673-6087.2024.05.10

Abstract

Abstract:

Colorectal cancer (CRC) is one of the most common malignant tumors of digestive system in the world. Epidemiological statistics showed that the global incidence of CRC ranked third among all cancer types and its mortality rate ranked second in 2020, while the reasons for the increased incidence are still not clear. At present, it is believed that the occurrence of CRC is a multi-factor and multi-step chronic process. Because the onset of CRC is insidious and the early detection rate is low, most patients are diagnosed in the middle and late stage as symptoms develop, which leads to poor prognosis. The average 5-year survival rate of CRC in China was 56.9%, which was the lowest among surrounding Asia-Pacific countries. CRC has become a huge threat to the life and health of Chinese citizens. Therefore, further understanding of prognosis biomarkers of CRC are important in promoting individualized treatment and improving the survival rate and quality of life in CRC patients. This article reviews the research progress on prognostic biomarkers for CRC to provide some inspiration for future treatment of CRC.

Key words: Colorectal cancer, Prognosis, Biomarkers, Monitoring

CLC Number:

R735.2

WANG Hongxiao, SU Qiying, YAN Hua. Research progress on prognostic biomarkers for colorectal cancer[J]. Journal of Internal Medicine Concepts & Practice, 2024, 19(05): 337-341.

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